RESUMO
We report on a family with typical clinical findings of Noonan syndrome associated with giant cell lesions in maxilla and mandible. We discuss the obvious clinical overlap between Noonan syndrome and Noonan-like/multiple giant cell lesion syndrome, and we give further clinical and molecular support that these two entities could be allelic conditions.
Assuntos
Granuloma de Células Gigantes/patologia , Síndrome de Noonan/patologia , Adolescente , Adulto , Cromossomos Humanos Par 12/genética , DNA/genética , Diagnóstico Diferencial , Saúde da Família , Feminino , Granuloma de Células Gigantes/genética , Haplótipos , Humanos , Masculino , Repetições de Microssatélites , Síndrome de Noonan/genética , Linhagem , SíndromeRESUMO
The use or not of drainage after elective cholecystectomy has been recently studied, and we will discuss the real incidence of the subhepatic biliary collection and its clinical significance. In this sense, we studied 20 patients with a mean age of 45 years (4 male and 16 female), submitted to elective cholecystectomy according to selective techniques patterned by our group, where we realized ligature of all vessels of the gallbladder bed, and subhepatic drainage. These patients receibed 99 mTc-DISIDA at the moment we closed the abdomen, and in a period of 24 and 48 hours we studied its presence in the subhepatic bed and in the drainage material. All the patients had not post-operative complications and none biliary drainage or subhepatic collection scanned. We concluded that using our preconized techniques, the subhepatic drainage is unnecessary after elective cholecystectomy.
