1.
Ther Drug Monit
; 8(1): 78-84, 1986.
Artigo
em Inglês
| MEDLINE
| ID: mdl-3961897
RESUMO
A simple, robust, high performance liquid chromatographic method for serum paracetamol determination in both the therapeutic and overdose concentration ranges is described. The within- and between-batch precision of the method was better than CV 5% at both micromolar and millimolar concentrations, and recovery of added paracetamol from drug-free serum exceeded 96%. No interference from any of the other drugs, drug metabolites, and dietary constituents tested was found. Performance data in the overdose concentration range has been compared with that from the enzymatic kit procedure, and results from the two assays showed good correlation (r = 0.97).
Assuntos
Acetaminofen/sangue , Acetaminofen/intoxicação , Cromatografia Líquida de Alta Pressão , Custos e Análise de Custo , Humanos , Indicadores e Reagentes , Cinética , Monitorização Fisiológica
2.
Thromb Haemost
; 42(3): 1069-70, 1979 Oct 31.
Artigo
em Inglês
| MEDLINE
| ID: mdl-505398