1.
Infect Immun
; 70(2): 1002-5, 2002 Feb.
Artigo
em Inglês
| MEDLINE
| ID: mdl-11796640
RESUMO
Recombinant adenylate cyclase toxoids are shown to deliver inserted foreign CD4(+)-T-cell epitopes into the major histocompatibility complex class II presentation pathway, inducing a specific CD4(+)-T-cell response in vivo and yielding in vitro stimulation of specific CD4(+) T cells at a 100-times-higher molar efficiency than the free peptide containing the epitope.