RESUMO
In 44 consecutive patients undergoing elective open heart surgery (OHS), serial electrocardiograms (ECG), vectorcardiograms (VCG), serum CPK, cardiac isoenzymes (CPKMB), and myocardial images using Tc-99m pyrophosphate were obtained, before and after the operation, for the detection of acute myocardial infarction (AMI). Twenty-nine patients developed one or more positive tests postoperatively. Two patients had positive myocardial scintiscans; both had other evidence of infarction. Conversely, the appearance of CPKMB, or new ECG and VCG changes, occurred frequently without evidence of infarction, and were not associated with the development of a positive scintiscan. The results show that false-negative results are infrequent in patients imaged early after OHS, and that cardiac surgical procedures do not cause a high incidence of false-positive scintigrams. Consequently, radionuclide imaging for AMI offers an important adjunct for excluding acute infarction following open heart surgery.
Assuntos
Procedimentos Cirúrgicos Cardíacos , Infarto do Miocárdio/etiologia , Cintilografia , Ensaios Enzimáticos Clínicos , Creatina Quinase/sangue , Difosfatos , Eletrocardiografia , Feminino , Humanos , Isoenzimas/sangue , L-Lactato Desidrogenase/sangue , Masculino , Infarto do Miocárdio/diagnóstico , Complicações Pós-Operatórias , Tecnécio , VetorcardiografiaRESUMO
Technetium-99m-polyphosphate was found to accumulate in two squamous cell carcinomas of the lung. In one case, microscopy and electron microscopy failed to demonstrate calcification in the tumor. Possible mechanism(s) of accumulation of polyphosphate in nonosseous tissues was reviewed.