Assuntos
Dermatite Ocupacional/epidemiologia , Hipersensibilidade a Drogas/epidemiologia , Indústria Farmacêutica/estatística & dados numéricos , Adulto , Alérgenos/efeitos adversos , Alérgenos/análise , Feminino , Humanos , Irlanda/epidemiologia , Masculino , Pessoa de Meia-Idade , Equipamentos de Proteção/efeitos adversosRESUMO
We present the case of a 30-year-old patient with pontine glioblastoma multiforme, World Health Organisation grade IV (WHO IV). This case is of particular interest in terms of the patient's use of social media as a medium of expression. This popular form of communication raises important clinical, ethical and social issues relating to confidentiality and the nature of the physician-patient relationship in a unique context.
Assuntos
Blogging , Neoplasias do Tronco Encefálico/psicologia , Glioblastoma/psicologia , Cuidados Paliativos na Terminalidade da Vida/psicologia , Cuidados Paliativos , Adulto , Humanos , Masculino , PonteRESUMO
Summary Very little is known about the aetiology of eccrine porocarcinoma (EP), a rare malignant sweat-gland tumour. Most reported cases have arisen de novo, or from a benign eccrine poroma. We report an unusual case, in which eccrine porocarcinoma arose at the exact site of pre-existing Bowen disease (BD).
Assuntos
Doença de Bowen/patologia , Porocarcinoma Écrino/patologia , Neoplasias Cutâneas/patologia , Neoplasias das Glândulas Sudoríparas/patologia , Diagnóstico Diferencial , Feminino , Humanos , Pessoa de Meia-IdadeRESUMO
Necrobiosis lipoidica diabeticorum (NLD) is an inflammatory skin disorder of unknown cause which can be seen in patients with diabetes mellitus. Various treatments, including immunosuppressive agents have been tried, without consistent efficacy. NLD is generally thought not to correlate well with tight diabetic control. Pancreas transplantation is the only widely and clinically used treatment that restores euglycemia in type I diabetic recipients. We report a case of resolution of NLD that had been unchanged for decades before pancreas after kidney transplantation. Another unique aspect of our case was that immunosuppression was discounted as a confounding factor, because the patient had been exposed to the same antirejection regimen for 3 years preceding the pancreas transplantation.