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1.
Cyborg Bionic Syst ; 5: 0103, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38617112

RESUMO

Soft grippers due to their highly compliant material and self-adaptive structures attract more attention to safe and versatile grasping tasks compared to traditional rigid grippers. However, those flexible characteristics limit the strength and the manipulation capacity of soft grippers. In this paper, we introduce a hybrid-driven gripper design utilizing origami finger structures, to offer adjustable finger stiffness and variable grasping range. This gripper is actuated via pneumatic and cables, which allows the origami structure to be controlled precisely for contraction and extension, thus achieving different finger lengths and stiffness by adjusting the cable lengths and the input pressure. A kinematic model of the origami finger is further developed, enabling precise control of its bending angle for effective grasping of diverse objects and facilitating in-hand manipulation. Our proposed design method enriches the field of soft grippers, offering a simple yet effective approach to achieve safe, powerful, and highly adaptive grasping and in-hand manipulation capabilities.

2.
Nat Prod Rep ; 40(3): 557-594, 2023 03 22.
Artigo em Inglês | MEDLINE | ID: mdl-36484454

RESUMO

Covering: up to 2022Streptomyces are ubiquitous in terrestrial and marine environments, where they display a fascinating metabolic diversity. As a result, these bacteria are a prolific source of active natural products. One important class of these natural products is the nonribosomal lipopeptides, which have diverse biological activities and play important roles in the lifestyle of Streptomyces. The importance of this class is highlighted by the use of related antibiotics in the clinic, such as daptomycin (tradename Cubicin). By virtue of recent advances spanning chemistry and biology, significant progress has been made in biosynthetic studies on the lipopeptide antibiotics produced by Streptomyces. This review will serve as a comprehensive guide for researchers working in this multidisciplinary field, providing a summary of recent progress regarding the investigation of lipopeptides from Streptomyces. In particular, we highlight the structures, properties, biosynthetic mechanisms, chemical and chemoenzymatic synthesis, and biological functions of lipopeptides. In addition, the application of genome mining techniques to Streptomyces that have led to the discovery of many novel lipopeptides is discussed, further demonstrating the potential of lipopeptides from Streptomyces for future development in modern medicine.


Assuntos
Produtos Biológicos , Daptomicina , Streptomyces , Lipopeptídeos , Streptomyces/metabolismo , Daptomicina/farmacologia , Daptomicina/química , Antibacterianos/química , Produtos Biológicos/farmacologia , Produtos Biológicos/metabolismo
3.
Nanotechnology ; 21(31): 315202, 2010 Aug 06.
Artigo em Inglês | MEDLINE | ID: mdl-20634572

RESUMO

A complete understanding of the interaction between electromagnetic radiation and semiconductor nanowires (NWs) is required in order to further develop a new generation of opto-electronic and photonic devices based on these nanosystems. The reduced dimensionality and high aspect ratio of nanofilaments can induce strong polarization dependence of the light absorption, emission and scattering, leading in some cases to the observation of optical antenna effects. In this work we present the first systematic study of polarized Rayleigh back-scattering from individual crystalline semiconductor NWs with known crystalline structure, orientation and diameters. To explain our experimental Rayleigh polar patterns, we propose a simple theory that relies on a secondary calculation of the volume-averaged internal electromagnetic fields inside the NW. These results revealed that the internal and emitted field can be enhanced depending on the polarization with respect to the NW axis; we also show that this effect strongly depends on the NW diameter.

4.
Nano Lett ; 8(5): 1341-6, 2008 May.
Artigo em Inglês | MEDLINE | ID: mdl-18422362

RESUMO

We report on investigations of the interaction of light with nanoscale antennae made from crystalline GaP nanowires (NWs). Using Raman scattering, we have observed strong optical antenna effects which we identify with internal standing wave photon modes of the wire. The antenna effects were probed in individual NWs whose diameters are in the range 40 < d < 300 nm. The data and our calculations show that the nature of the backscattered light is critically dependent on the interplay between a photon confinement effect and bulk Raman scattering. At small diameter, d < 65 nm, the NWs are found to act like a nearly perfect dipole antenna and the bulk Raman selection rules are masked leading to a polarized scattering intensity function I R approximately cos4 theta. Underscoring the importance of this work is the realization that a fundamental understanding of the "optical antenna effect" in semiconducting NWs is essential to the analysis of all electro-optic effects in small diameter filaments.


Assuntos
Cristalização/métodos , Gálio/química , Nanotecnologia/métodos , Nanotubos/química , Nanotubos/ultraestrutura , Fosfinas/química , Semicondutores , Condutividade Elétrica , Luz , Substâncias Macromoleculares/química , Teste de Materiais , Conformação Molecular , Tamanho da Partícula , Espalhamento de Radiação
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