[Determination of total organic acids and salicylic acid in extract of Radix isatidis].

OBJECTIVE: To develop a quantitative method for determination of the total organic acids and salicyclic acid in the extract of Radix Isatidis. METHOD: The total organic acids were determined by acid-base titration and the salicylic acid was determined by HPLC. RESULT: It was shown that contents of total organic acids and salicylic acid in the extract of Radix Isatidis were 13.0% and 0.22%, respectively. CONCLUSION: The method can control the quality of this extract effectively and accurately.