RESUMO
Ex novo Kaposi's Sarcoma 4 months after renal transplantation in a young patient is described. Progression of the tumoral lesions has been observed during combined immunosuppressive treatment with Prednisone, Azathioprine and Cyclosporin. Stopping Azathioprine and Cyclosporin as well as reducing Prednisone prevented new lesions and made the preexistent skin lesions less extensive. Clinical case, possible pathogenesis and therapeutic strategies are discussed.
Assuntos
Imunossupressores/efeitos adversos , Transplante de Rim , Sarcoma de Kaposi/induzido quimicamente , Neoplasias Cutâneas/induzido quimicamente , Adulto , Humanos , Masculino , Sarcoma de Kaposi/patologia , Neoplasias Cutâneas/patologiaRESUMO
The authors intended verifying the effectiveness of natural beta-interferon in the treatment of metastatic pleural effusion from breast's cancer. 24 patient, with an average age of 54, were studied. The objective responses were: 2 Complete Responses, 8 Partial Responses, 6 Stationarity and 5 Progression. The responses seem independent from the association of systemic treatment. Clinical response has been observed in patients with initial pleural effusion less than or equal to 1000 cc.