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Acta Trop ; 219: 105893, 2021 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-33872586

RESUMO

Over 90% of schistosomiasis infections occur in sub-Saharan Africa. A rapid ICT test would be a cheap and easy tool that could be used also in the field. We preliminarily evaluated the performance of a new Schistosoma black-latex based IgG-IgM ICT (Black-ICT) on serum samples. The results indicate a high sensitivity (98.0%) but the specificity depends on the application of a cut-off value that can discriminate between positive and negative samples. Considering a possible direct application of this test on blood from finger prick, the results are promising, providied that a signal intensity scale is developed, guiding the result interpretation.


Assuntos
Testes Imunológicos/métodos , Schistosoma/isolamento & purificação , Animais , Anticorpos Anti-Helmínticos/sangue , Humanos , Imunoglobulina G/sangue , Schistosoma/imunologia , Sensibilidade e Especificidade
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