RESUMO
Abscess formation secondary to chronic urethritis of the posterior male urethra caused by Neisseria gonorrhoeae has become an atypical and rare urological complication. Periurethral abscess formation has been reported to be associated with gonococcal infections, but in such rare cases a delay in the diagnosis of gonococcal infection seems to have been the cause for this periurethral complication. A case with a primary diagnosis of periurethral abscess with N. gonorrhoeae infection is reported--successful treatment included transurethral incision and antibiotic therapy.
Assuntos
Abscesso Abdominal , Gonorreia , Doenças Uretrais , Abscesso Abdominal/diagnóstico , Abscesso Abdominal/terapia , Gonorreia/diagnóstico , Gonorreia/terapia , Humanos , Masculino , Pessoa de Meia-Idade , Doenças Uretrais/diagnóstico , Doenças Uretrais/terapiaRESUMO
CD44s, E-cadherin and PCNA play an important role in the tumorigenesis of renal cell carcinoma (RCC), although their significance in the clinical progression of RCC is still not clear. In n = 137 cases of operatively resected RCC the expression of CD44s, E-cadherin and PCNA was semiquantitatively analyzed by the APAAP immunohistochemical method. The mean observation period of the n = 74 (54%) of patients with no evidence of disease was 52.6 months and for the n = 63 (46%) patients with progressive disease was 18.7 months. The mean progression free period occurring with absent or low levels of CD44s and PCNA expression was 79 and 118+ months, and with strong expression was 12 and 18 months (p < 0.001), respectively. With strong E-cadherin expression the progression free period was 110+ months, and with low expression 61 months (p = 0.01). A high CD44s/E-cadherin ratio and an above average PCNA expression were identified as independent prognostic parameters for the progression tendency of RCC.
