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World J Gastroenterol ; 20(25): 8304-8, 2014 Jul 07.
Artigo em Inglês | MEDLINE | ID: mdl-25009408

RESUMO

A variety of clinical manifestations are associated directly or indirectly with tuberculosis. Among them, haematological abnormalities can be found in both the pulmonary and extrapulmonary forms of the disease. We report a case of immune thrombocytopenic purpura (ITP) associated with intestinal tuberculosis in a liver transplant recipient. The initial management of thrombocytopenia, with steroids and intravenous immunoglobulin, was not successful, and the lack of tuberculosis symptoms hampered a proper diagnostic evaluation. After the diagnosis of intestinal tuberculosis and the initiation of specific treatment, a progressive increase in the platelet count was observed. The mechanism of ITP associated with tuberculosis has not yet been well elucidated, but this condition should be considered in cases of ITP that are unresponsive to steroids and intravenous immunoglobulin, especially in immunocompromised patients and those from endemic areas.


Assuntos
Hospedeiro Imunocomprometido , Imunossupressores/efeitos adversos , Enteropatias/imunologia , Transplante de Fígado/efeitos adversos , Púrpura Trombocitopênica Idiopática/imunologia , Tuberculose Gastrointestinal/imunologia , Idoso , Antituberculosos/uso terapêutico , Biópsia , Colonoscopia , Humanos , Imunoglobulinas Intravenosas/uso terapêutico , Enteropatias/diagnóstico , Enteropatias/tratamento farmacológico , Enteropatias/microbiologia , Masculino , Púrpura Trombocitopênica Idiopática/diagnóstico , Púrpura Trombocitopênica Idiopática/tratamento farmacológico , Púrpura Trombocitopênica Idiopática/microbiologia , Esteroides/uso terapêutico , Tomografia Computadorizada por Raios X , Resultado do Tratamento , Tuberculose Gastrointestinal/diagnóstico , Tuberculose Gastrointestinal/tratamento farmacológico , Tuberculose Gastrointestinal/microbiologia
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