Association between Chronic Misophonia-Induced Stress and Gastrointestinal Pathology in Children-A Hypothesis.

Misophonia is a neurophysiological disorder with behavioral implications, is complex and multifactorial in origin, and is characterized by an atypical and disproportionate emotional response to specific sounds or associated visual stimuli. Triggers include human-generated sounds, mainly sounds related to feeding and breathing processes, and repetitive mechanical sounds. In response to the triggering stimulus, the patient experiences immediate, high-intensity, disproportionate physical and emotional reactions that affect their quality of life and social functioning. The symptoms of misophonia can occur at any age, but onset in childhood or adolescence is most common. Affected children live in a constant state of anxiety, suffer continuous physical and emotional discomfort, and are thus exposed to significant chronic stress. Chronic stress, especially during childhood, has consequences on the main biological systems through the dysregulation of the hypothalamic-pituitary-adrenal axis, including the gastrointestinal tract. Here, we provide arguments for a positive correlation between misophonic pathology and gastrointestinal symptoms, and this hypothesis may be the starting point for further longitudinal studies that could investigate the correlations between these childhood vulnerabilities caused by misophonia and their effect on the gastrointestinal system. Further research to study this hypothesis is essential to ensure correct and timely diagnosis and optimal psychological and pharmacological support.

The Role of Personality Dimensions in the Etiopathogenesis of Primary Hypertension.

Background: Although hypertension is the most important cardiovascular risk factor, we still do not understand all the factors that contribute to the disease onset. The aim of this study was to examine the association between personality dimensions and primary hypertension. Methods: In total, 310 participants were recruited in a case-control design. The association of personality dimensions with primary hypertension was examined in normotensive (n = 156) and hypertensive (n = 120) patients following assessment of the 5 personality dimensions with the DECAS Personality Inventory. A binary logistic regression model was used to assess the predictive value of personality traits for hypertension, controlling for recognized confounders such as age, gender, obesity, smoking history, parental history of hypertension, and education. Results: Low or very low emotional stability was almost twice as frequent in the hypertensive group (71.7%) as in the normotensive study population (43.5%). The binary logistic regression model showed that low emotional stability is a significant predictor for hypertension, the risk of being hypertensive decreasing by 7% with each point increase on the emotional stability score. Very low or low emotional stability increased the odds of being hypertensive by 3.55 times (odds ratio: 3.55, 95% CI: 2.18-9.35, P < .001). No association between the severity of hypertension and personality traits was found. Conclusions: People with low emotional stability/high neuroticism have more than 3-fold increased odds of developing primary hypertension. The assessment of personality traits could be used as a tool to identify individuals at risk to develop primary hypertension as well as patients with primary hypertension where psychotherapy could be of potential value. This study highlights the need for further research, in order to establish effective, patient-oriented prevention strategies and treatment options.

Occupational Stress and Personality in Medical Doctors from Romania.

Occupational stress amongst doctors has been intensively studied as doctors are exposed to several stress factors daily. The purpose of this study was to investigate if there are associations between personality dimensions and the factors that generate stress at work. We conducted a cross-sectional study of 280 medical doctors from Romania between February 2021 and September 2021 who were evaluated using the DECAS and ASSET Scales. Our results showed that the agreeableness and emotional stability dimensions of personality, according to the Big Five model, were statistically associated with work relationships (A p < 0.0001; ES p = 0.0005), work-life balance (A p = 0.008; ES p = 0.01), overload (A p = 0.01; ES p = 0.001), job security (A p < 0.0001; ES p = 0.002), job control (A p = 0.001; ES p = 0.009), resources and communication (A p = 0.0002; ES p < 0.0001), and job conditions (A p = 0.005; ES p = 0.03). The conscientiousness dimension was statistically associated with job control (p = 0.02). Doctors from different specialties experienced stress differently, with psychiatrists and doctors from preclinical specialties reporting the lowest levels of stress. Internists and surgeons reported higher levels of stress. This study showed that the dimensions of agreeableness and emotional stability were both associated with variables indicative of the level of stress felt at work.

The Clinical, Biological, Psychological and Psychiatric Impact of the Diagnosis of Breast Cancer in Women.

OBJECTIVE: Psychosocial factors are correlated with the risk of breast cancer, by the lack of externalization of feelings and aggressive tendencies, or with a negative prognosis, by the presence of a high level of stress and reduced coping abilities. Impairment of psychological status should be assessed early to identify quantifiable psychooncological changes, such as depression, anxiety, and self-esteem. These indicators, measured in this study, may become psychometric markers for predicting the existence of the neoplastic process, prior to histopathological evaluations. METHODS: 58 patients diagnosed with breast cancer and in different stages of evolution and 61 breast lumps patients were evaluated for depression, anxiety and self-esteem. RESULTS: The correlation of depression and anxiety levels according to the evolutionary stage of the disease was as follows: in stage I cases of severe depression with significant anxiety predominate, in stage II mild depression predominates with insignificant anxiety, in stage III depression predominates moderate with significant anxiety, while in stage IV moderate depression with significant anxiety predominates. CONCLUSIONS: The presence of significant anxiety in the uncertainty phase and the anxious-depressive clinical picture can be an alarm signal for the initiation of specific psychotherapeutic strategies, to increase the adaptive potential and resilience to the disease to ensure a therapeutic collaboration of the patient by increasing adherence and compliance. the proposed therapeutic plan. Relatively sudden anxiety in a young woman, risk factors for breast cancer, and deficient cognitive impairment require intensified clinical and paraclinical investigations to confirm early oncological diagnosis.

The Relationship between Personality, Motivation and Academic Performance at Medical Students from Romania.

The academic and health system requirements are constantly growing due to the continuous development of this sector. Therefore, it is important to investigate the structural factors that improve performance in the medical system. The aim of our pilot study is to analyze if there are associations or correlations between personality and motivation and the results obtained for the National Residency Exam of Romanian medical graduates. We conducted a prospective pilot study on 179 medical students from George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Romania between February 2021 and December 2021, who were evaluated by the DECAS, IM, and SPM scale. Our results showed that all the dimensions of personality according to the Big Five Model, which include openness (OR = 0.392, p = 0.01), extraversion (OR = 0.512, p = 0.03), conscientiousness (OR = 3.671, p = 0.004), agreeableness (OR = 2.791, p = 0.07), and emotional stability (OR = 4.863, p = 0.0003), are statistically associated with the result obtained. Motivation also plays an important role in academic achievements, through motivational persistence and motivational involvement which correlates with the conscientiousness dimension and the result obtained. This study confirms that both personality structure and motivation are associated or correlated with the academic results of medical students and represent a starting point for future research.

The Relationship between Emotional Stability, Psychological Well-Being and Life Satisfaction of Romanian Medical Doctors during COVID-19 Period: A Cross-Sectional Study.

Due to the COVID-19 pandemic, as well as the fast progression of modern society, occupational stress has recently reached alarming levels with consequences for doctors' psychological well-being. The aim of this study was to analyze the relationship among emotional stability, psychological well-being, and life satisfaction of medical doctors. We conducted a cross-sectional study on 280 medical doctors from Romania between February 2021 and September 2021, in the period between the third and fourth pandemic waves, who were evaluated by the DECAS, ASSET, and Satisfaction with Life scales. Our results showed that emotional stability is negatively correlated with psychological well-being (r = −0.526, p < 0.000) and positively correlated with life satisfaction (r = 0.319, p < 0.0001). Between psychological well-being and life satisfaction, we found a negative correlation (r = −0.046, p < 0.001). This study shows that there is a correlation among emotional stability, psychological well-being, and life satisfaction, which is why it can be considered that Romanian doctors have generated coping mechanisms during the COVID-19 pandemic.

Dependent personality features in a complex case of borderline personality disorder.

Borderline personality disorder is a complex disease model as it encompasses a diversity of pathological personality traits and psychopathological symptoms. It is not surprising, therefore, that it is often manifested by personality disorders across all three clusters and accompanied by other mental (Axis I) disorders. This melange makes both psychological treatment and pharmacotherapy especially challenging, and this paper describes the case of a particularly complex case of a 33-year-old Romanian patient, who has a history of severe deprivation in childhood, mood and substance use disorder in association with borderline pathology. In the course of treatment from many sources and interventions, it has become clear that dependence is a key component of the pathology and has been rewarded with a degree of success in management. Copyright © 2016 John Wiley & Sons, Ltd.

Narcissistic biographies--third age self-transcendence abilities.

Narcissistic traits interfere in the process of self-determination and the individual motivational strategies of human beings. The grandiose and vulnerable narcissistic personality subtypes have difficulties in their education, interpersonal relationships and quality of life. The latter is also affected by ageing, whose attributes influence, above all, one's self-esteem, especially in women. Though very fearful of suffering and death, narcissists have a powerful desire to overcome them by cultivating their grandiosity, especially through the mystical and paranormal experiences they relate. The spiritual means of transcending one's self, including the components of magical thinking, can prevent the destruction of self-esteem in narcissists in their third-age.