[Changes in the afferent activity of the vagus nerve and the rectal temperature in rats following Escherichia coli endotoxin administration]. / Izmeneniia afferentnoi impul'satsii v bluzhdaiushchikh nervakh i rektal'noi temperatury u krys posle vvedeniia éndotoksina Escherichia coli.

In anaesthetised rats, i.p. administration of the Echerichia coli lipopolysaccharide in doses 5 mcg/kg (LPS) increased afferent activity of the cervical vagus, whereas 100 and 1000 mcg/kg doses inhibited the afferent discharges. Pyrogen-free saline (PFS) did not alter the activity. Rectal temperature (RT) was decreased by the PFS and by large doses of the LPS. Sodium salicylate administration prevented the effects.