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Magn Reson Med ; 4(4): 380-4, 1987 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-3035320

RESUMO

An electron paramagnetic resonance image was measured for the first time from in vivo field gradient spectra of a living murine tumor (Cloudman S-91 melanoma in the tail of a DBA-2J mouse) using the paramagnetic nitroxide imaging agent 3-carboxamido-2,2,5,5-tetramethylpyrroline-1-oxyl injected into the tail vein. The experiments were accomplished at L-band frequency (1.55 GHz) with a single-turn flat-loop coil. A cross-sectional image was obtained perpendicular to the tail axis, which clearly distinguished features to the submillimeter resolution level.


Assuntos
Espectroscopia de Ressonância de Spin Eletrônica , Neoplasias Experimentais/diagnóstico , Animais , Óxidos N-Cíclicos , Melanoma/diagnóstico , Camundongos , Camundongos Endogâmicos DBA , Transplante de Neoplasias , Marcadores de Spin
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