RESUMO
The absolute count of different types of granulocytes was determined and their ultrastructure was studied in the blood of rabbits immunized with bovine serum albumin. Both the primary and repeated antigen administration were followed by regular quantitative and qualitative changes in neutrophils, basophils, and eosinophils whose degree and character were determined by the stage of the immune response formation.
Assuntos
Reações Antígeno-Anticorpo , Glucocorticoides/imunologia , Granulócitos/imunologia , Imunização , Leucócitos/imunologia , Animais , Granulócitos/ultraestrutura , Imunização Secundária , Contagem de Leucócitos , Coelhos , Soroalbumina Bovina/administração & dosagem , Fatores de TempoRESUMO
As a result of immunization and reimmunization with bovine serum albumin there was a change of the number and correlation of various morphologically identifyable species of lymphocytes in the blood of rabbits. Regular submicroscopic changes in the nucleus and organoids of the cytoplasm pointing to increased functional activity of these cells were revealed at the ultrastructural level in many circulating lymphocytes belonging to various populations.