1.
Org Lett
; 5(25): 4771-4, 2003 Dec 11.
Artigo
em Inglês
| MEDLINE
| ID: mdl-14653670
RESUMO
The diastereoselective synthesis of hydrazinocyclopentenes 6 or 7 can be achieved in a straightforward manner from Diels-Alder adduct 4 using an acid-catalyzed rearrangement or a palladium-catalyzed allylic substitution reaction. In the latter case, enantioenriched compounds with ee values up to 58% can be obtained when an appropriate chiral ligand is used. [reaction: see text]
2.
J Am Chem Soc
; 124(41): 12098-9, 2002 Oct 16.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12371841
RESUMO
The Ir-catalyzed asymmetric hydroboration of bicyclic hydrazines with ee and chemical yields up to 64% is reported. The switch from rhodium to iridium leads systematically to opposite enantiomers in this desymmetrization reaction.