[Comparation of constitutions between raw Psoralea corylifolia L. and processed one].

OBJECTIVE: To study the processing material foundation of Psoralea corylfolia L. and compare the content of psoralen, isopsoralen and microelement between raw Psoralea corylifolia L. and processed one. METHODS: The content of psoralen, isopsoralen and microelement were obtained by HPLC-gradient elution and ICP-AES. RESULTS: The content of psoralen, isopsoralen and microelement Mn, Ca, Mg, Fe, Zn were raising, but the change of that of microelement Cu was not obvious. CONCLUSION: The content of effective composition of Psoralea corylifolia L. is raised by Lei-Gong method and the biological activity is improved simultaneously.