[Treatment of HPV-positive CIN1 and CIN2 with intralesion administration of human interferon from fibroblasts associated with DTC (diathermal coagulation) of the cervical portio]. / Trattamento intralesionale della CIN1 e CIN2 (con positività all'HPV) con interferone umano da fibroblasti associato a DTC della portio.

The aim of this study was to draw attention to the efficacy of the therapeutic association of intralesional beta-IFN-DTC of the portio in HPV-positive CIN1 and CIN2 in 25 women aged between 21 and 41 years of age. Control tests after the completion of treatment showed complete recovery from CIN and the disappearance of the virus. Side effects were minimal and in no instance did they affect patients' normal activities or lead to an interruption of therapy. No cases of recidivation or relapse were reported 12 months after the completion of therapy.

[Decapeptyl 3.57mg in the therapy of the fibromatous uterus. Authors' contribution]. / Decapeptyl 3,75 mg nella terapia dell'utero fibromatoso. Nostro contributo.

Thirty women in their reproductive age who were diagnosed for leiomyomata uteri were treated for 6 months with Triptorelin slow release, 3.75 mg, every 28 days, i.m. The results obtained were highly satisfactory and were confirmed by ultrasound scanning and clinical examination. The drug was extremely well tolerated by patients and the side-effects reported never required the interruption of treatment.

[Vaginal topical chemical contraception with C-film]. / Contraccezione chimica topica vaginale con C-film.

PIP: C-film is a plastic sheet of 4 sq cm, 28% of which is made up of a spermicidal agent; the plastic leaf is folded and introduced deep into the vagina; its spermicidal action lasts 1-2 hours. Tests conducted in Europe and in the U.S. have shown C-film to be highly acceptable, safe, and to have a Pearl index of 2.5. The authors investigated the use of C-film on 37 patients, for a total of 924 woman-months. There were only 3 pregnancies, of which 1 was due to incorrect use of the device, and 6 cases of vaginitis which resolved spontaneously. This contraceptive method may be particularly recommended to young women and to women over 40 as an alternative to hormonal contraception or the IUD.^ieng