Temporal distortion for angry faces: Testing visual attention and action preparation accounts.

When asked to judge the duration of a face people typically overestimate the duration of angry compared with neutral faces. A novel feature of the current research was the inclusion of secondary manipulations designed to distort timing performance namely the effects of visual cues (Experiment 1) and action preparedness (Experiment 2). Furthermore, to establish whether the effects are multiplicative with duration, the effects were examined across two duration ranges (200-800 and 400-1,600 ms). Visual cues and instructions to prepare to act increased the tendency to judge faces as lasting longer. Experiment 1 revealed an unexpected underestimation effect for angry faces presented for short durations (200-800 ms). However, the effect was not replicated in Experiment 2 where the results were generally consistent with either an increase the speed of a pacemaker mechanism that resides within an internal clock or the widening of an attentional gate-the temporal overestimation effect for angry faces grew in magnitude from the short to long duration. Experiment 2 also showed that the temporal overestimation for angry faces was reduced in magnitude when participants were asked to prepare to either push or pull a joystick.

Does the use of additional X-ray beam filtration during cine acquisition reduce clinical image quality and effective dose in cardiac interventional imaging?

The impact of spectral filtration in digital ('cine') acquisition was investigated using a flat panel cardiac interventional X-ray imaging system. A 0.1-mm copper (Cu) and 1.0-mm aluminium (Al) filter added to the standard acquisition mode created the filtered mode for comparison. Image sequences of 35 patients were acquired, a double-blind subjective image quality assessment was completed and dose-area product (DAP) rates were calculated. Entrance surface dose (ESD) and effective dose (E) rates were determined for 20- and 30-cm phantoms. Phantom ESD fell by 28 and 41 % and E by 1 and 0.7 %, for the 20- and 30-cm phantoms, respectively, when using the filtration. Patient DAP rates fell by 43 % with no statistically significant difference in clinical image quality. Adding 0.1-mm Cu and 1.0-mm Al filtration in acquisition substantially reduces patient ESD and DAP, with no significant change in E or clinical image quality.

Can ethics survive the onslaught of science?

The issue on which I will attempt to cast some light is certainly not novel. It has been ongoing for many years but the pace of scientific progress is gathering and the retreat of ethical barriers is relentless. I will illustrate my thesis by using examples of legal decisions from the realm of assisted human procreation and the posthumous conception of children from the sperm of deceased fathers e.g., the cases of Diane Blood, Parpalaix and Nikolas Coltan Evans. I will also highlight the recent case of Ashley X, a nine year old girl whose parents authorised radical medical treatment to arrest her development. I will argue that the law is being driven to roll back the ethical standards derived from our legacy of Natural Law by the imperatives of human rights e.g., the right to found a family, and the quest for patient autonomy. These are both admirable goals but fulfilling these goals comes at a cost to cherished ethical values e.g., that children are conceived by living fathers and that indulging the personal desires of every individual cannot forever be encompassed. As our legislators and courts chip away at our core network of ethical values, are they replacing them with equivalent values or do their decisions amount to a hollowing out of the core ethical values e.g., Thou shalt not kill and that human life is sacrosanct? Yet abortion is legal in many countries as is euthanasia. Paradoxically there is legislative protection for embryos by limiting experimentation on these clusters of cells. How do you construct a rational ethical framework with such blatant legal inconsistencies in the protection of human life? The sanctity of human life constitutes one of the fundamental pillars of ethical values which, in turn, support much more of the structure of ethics. Is a society that permits freezing the development of a nine year old child not a society whose ethics are so compromised that it is doomed to defend an ever diminishing mass of ethical values? Is there a core of ethics which is sacrosanct or is every ethical frontier fair game for invasion? Are the Ethics Committees, which approve and monitor research in the field of bioethics in Universities. Hospitals and laboratories failing in their duty as gatekeepers? They are after all the first line of defence for the survival of crucial ethical values. Can we continue to indulge the whims and needs of every individual under the guise of human rights or patient autonomy? Can a civilised society endure as such with an ever diminishing mass of ethical values?

The social, moral & ethical issues raised by nanotechnology in the field of medicine.

The areas in medicine that are and will be influenced by nanoscale science and technology are stem cell research, genetic modification of human beings and the construction of artificial organisms. A non-negotiable moral imperative is the fact that the law is under an obligation to uphold the sanctity and integrity of the human genome which encapsulates humankind's basic genetic inheritance and thereby the human heritage of our species. The research possibilities opened up by nanoscience will push the current boundaries of life forms, because they alter life forms at their most basic (viz genetic) level. They empower scientists to create novel life forms that would not otherwise exist and they combine aspects of different life forms that would not otherwise be integrated. These groundbreaking areas of research place the scientists and their work in an area of moral quicksands. Research involving human design and modification places those scientists in a domain where current morality indicates they do not belong. They are literally 'playing God'.