[Risk factors for arterial disease]. / Factores de riesgo de enfermedad arterial.

The risk factors of arterial disease (FREA) predict a future damage over the vascular system of the human body. Its detection are considered a key for the diagnostic as well as for the preventive and even curative strategies. For a long time, scientist considered those factors originated as a consecuence of large studies during the middle of the last century, with current validity up to our days. A simple classification spoke of them as traditionals. Further investigations described the so called new or emergents.factors that where joint together accordingly to their actions: coagulation factors, psicosocial, inflamatories and infectious. A recent classification, taking into account the type of impact, divided them into; causatives, predisposals and conditionals. Also, it was described a mechanism, the oxidative power, with consecuences over the endothelium, in the last part of the process. Before, another mechanism was described: the insulin resistance and the hiperinsulinism, bases for the Metabolic Syndrome, that includes a number of traditional risk factors.

[Annex: Prevalence of insulin resistance and its association with type 2 diabetes and other cardiovascular risk factors]. / Anexo. Prevalencia de la insulinoresistencia y su asociación con diabetes tipo 2 y otros factores de riesgo cardiovascular.

We present the results of an epidemiological research undertaken in the province of Córdoba (Argentina) with the aim of studying insulin-resistance (IR) in relation to the increased risk for diabetes and its association with risk factors of arterial disease (RFAD). Overall, there were 1413 subjects between 20 and 70 years of age, from both sexes (Dean Funes 18885 inhabitants; sample 715; Oncativo 13880 inhabitants; sample 696). We studied traditional arterial risk factors (hypertension, diabetes, dyslipidemia, obesity, sedentary life, smoking). To evaluate IR we used the homeostasis model assessment (HOMA-IR). We found a high prevalence of IR clearly related to the traditional (RFAD), thus placing these populations, representatives of national ones, among the western populations at high risk for arterial disease.

[Body training and insulin resistance in two rural communities of Cordoba - Argentina]. / Actividad fisica e insulinorresistencia en dos comunidades rurales de Cordoba - Argentina.

UNLABELLED: From the AF, the smaller risk is controversial. The influence of the general and environmental components on IR is not know in a satisfactory way. OBJECTIVES: The influence of AF on the prevail IR in two rural communities of Córdoba with different fenotipical configuration and IR risk. MATERIAL AND METHODS: Transverse study (survey, clinical and biochemical checkup) over 1143 people of Oncativo community (ON) and Dean Funes (DF), inclusion: n = 673 (30-60 years old) Normal ECG, no diabetics. Sorts AF according to the spend of calories (Kcal/sem): a) sedentary (< 500), b) low (5001-1000), c) regular (1001-2500), and d) High (> 2500). IR is HOMA > 2.5; where [HOMA = (Glucemia * Insulina)/ 4.5]. RESULTS: AF: 31.4% sedentary, 20.2% low, 26.3% regular and 22.1% high. 16.5% IR in ON opposite 34.8% en DF (P < 0.001), IR in ON 8.2% with AF high opposite 18.8% the rest (P = 0.032), 36.8% and 34.2% like in DF (P = 0.67). With the adjusted results for age and community it was found less IMC (P = 0.002) and waist circumference (P = 0.042) than the most category of AF. The blood pressure had not a meaningful change, lipid profile or HOMA depending of AF. CONCLUSION: if a benefit of AF over IR exists, it will be conditioned for genetics and environmental primaries determiners.

Factores de riesgo de enfermedad arterial. / [Risk factors for arterial disease]

The risk factors of arterial disease (FREA) predict a future damage over the vascular system of the human body. Its detection are considered a key for the diagnostic as well as for the preventive and even curative strategies. For a long time, scientist considered those factors originated as a consecuence of large studies during the middle of the last century, with current validity up to our days. A simple classification spoke of them as traditionals. Further investigations described the so called new or emergents.factors that where joint together accordingly to their actions: coagulation factors, psicosocial, inflamatories and infectious. A recent classification, taking into account the type of impact, divided them into; causatives, predisposals and conditionals. Also, it was described a mechanism, the oxidative power, with consecuences over the endothelium, in the last part of the process. Before, another mechanism was described: the insulin resistance and the hiperinsulinism, bases for the Metabolic Syndrome, that includes a number of traditional risk factors.

Anexo. Prevalencia de la insulinoresistencia y su asociación con diabetes tipo 2 y otros factores de riesgo cardiovascular. / [Annex: Prevalence of insulin resistance and its association with type 2 diabetes and other cardiovascular risk factors]

We present the results of an epidemiological research undertaken in the province of Córdoba (Argentina) with the aim of studying insulin-resistance (IR) in relation to the increased risk for diabetes and its association with risk factors of arterial disease (RFAD). Overall, there were 1413 subjects between 20 and 70 years of age, from both sexes (Dean Funes 18885 inhabitants; sample 715; Oncativo 13880 inhabitants; sample 696). We studied traditional arterial risk factors (hypertension, diabetes, dyslipidemia, obesity, sedentary life, smoking). To evaluate IR we used the homeostasis model assessment (HOMA-IR). We found a high prevalence of IR clearly related to the traditional (RFAD), thus placing these populations, representatives of national ones, among the western populations at high risk for arterial disease.

Actividad fisica e insulinorresistencia en dos comunidades rurales de Cordoba - Argentina. / [Body training and insulin resistance in two rural communities of Cordoba - Argentina]

From the AF, the smaller risk is controversial. The influence of the general and environmental components on IR is not know in a satisfactory way. OBJECTIVES: The influence of AF on the prevail IR in two rural communities of Córdoba with different fenotipical configuration and IR risk. MATERIAL AND METHODS: Transverse study (survey, clinical and biochemical checkup) over 1143 people of Oncativo community (ON) and Dean Funes (DF), inclusion: n = 673 (30-60 years old) Normal ECG, no diabetics. Sorts AF according to the spend of calories (Kcal/sem): a) sedentary (< 500), b) low (5001-1000), c) regular (1001-2500), and d) High (> 2500). IR is HOMA > 2.5; where [HOMA = (Glucemia * Insulina)/ 4.5]. RESULTS: AF: 31.4

sedentary, 20.2

low, 26.3

regular and 22.1

high. 16.5

IR in ON opposite 34.8

en DF (P < 0.001), IR in ON 8.2

with AF high opposite 18.8

the rest (P = 0.032), 36.8

and 34.2

like in DF (P = 0.67). With the adjusted results for age and community it was found less IMC (P = 0.002) and waist circumference (P = 0.042) than the most category of AF. The blood pressure had not a meaningful change, lipid profile or HOMA depending of AF. CONCLUSION: if a benefit of AF over IR exists, it will be conditioned for genetics and environmental primaries determiners.

Anexo: prevalencia de la insulinoresistencia y su asociación con diabetes tipo 2 y otros factores de riesgo cardiovascular / Annex: prevalence of insulin resistance and its association with type 2 diabetes and other cardiovascular risk factors

Se presentan los resultados de una investigación epidemiológica en la provincia de Córdoba (RA) con el objetivo de estudiar la insulinoresistencia (IR) en relación a riesgo aumentado para diabetes y su asociación con los FREA. En total fueron 1413 personas entre 20 y 70 años de edad, de ambos sexos (Deán Funes 18885 habitantes; muestra 715; Oncativo 13880 habitantes; muestra 696). Se estudiaron los factores de riesgo arterial tradicionales (HTA, Dia; DPD, Ob, Sed, Tab). Para valorar insulinorresistencia (IR) se utilizó el homeostasis model assesment (HOMA - IR). Se constató alta prevalencia de IR y clara asociación con los FREA tradicionales, colocando a estas poblaciones, representativas de las nacionales, dentro de las poblaciones occidentales de alto riesgo de enfermedad arterial.(AU)

Anexo. Prevalencia de la insulinoresistencia y su asociación con diabetes tipo 2 y otros factores de riesgo cardiovascular / [Annex: Prevalence of insulin resistance and its association with type 2 diabetes and other cardiovascular risk factors]

We present the results of an epidemiological research undertaken in the province of Córdoba (Argentina) with the aim of studying insulin-resistance (IR) in relation to the increased risk for diabetes and its association with risk factors of arterial disease (RFAD). Overall, there were 1413 subjects between 20 and 70 years of age, from both sexes (Dean Funes 18885 inhabitants; sample 715; Oncativo 13880 inhabitants; sample 696). We studied traditional arterial risk factors (hypertension, diabetes, dyslipidemia, obesity, sedentary life, smoking). To evaluate IR we used the homeostasis model assessment (HOMA-IR). We found a high prevalence of IR clearly related to the traditional (RFAD), thus placing these populations, representatives of national ones, among the western populations at high risk for arterial disease.

Factores de riesgo de enfermedad arterial / [Risk factors for arterial disease]

The risk factors of arterial disease (FREA) predict a future damage over the vascular system of the human body. Its detection are considered a key for the diagnostic as well as for the preventive and even curative strategies. For a long time, scientist considered those factors originated as a consecuence of large studies during the middle of the last century, with current validity up to our days. A simple classification spoke of them as traditionals. Further investigations described the so called new or emergents.factors that where joint together accordingly to their actions: coagulation factors, psicosocial, inflamatories and infectious. A recent classification, taking into account the type of impact, divided them into; causatives, predisposals and conditionals. Also, it was described a mechanism, the oxidative power, with consecuences over the endothelium, in the last part of the process. Before, another mechanism was described: the insulin resistance and the hiperinsulinism, bases for the Metabolic Syndrome, that includes a number of traditional risk factors.

Anexo: prevalencia de la insulinoresistencia y su asociación con diabetes tipo 2 y otros factores de riesgo cardiovascular / Annex: prevalence of insulin resistance and its association with type 2 diabetes and other cardiovascular risk factors

Se presentan los resultados de una investigación epidemiológica en la provincia de Córdoba (RA) con el objetivo de estudiar la insulinoresistencia (IR) en relación a riesgo aumentado para diabetes y su asociación con los FREA. En total fueron 1413 personas entre 20 y 70 años de edad, de ambos sexos (Deán Funes 18885 habitantes; muestra 715; Oncativo 13880 habitantes; muestra 696). Se estudiaron los factores de riesgo arterial tradicionales (HTA, Dia; DPD, Ob, Sed, Tab). Para valorar insulinorresistencia (IR) se utilizó el homeostasis model assesment (HOMA - IR). Se constató alta prevalencia de IR y clara asociación con los FREA tradicionales, colocando a estas poblaciones, representativas de las nacionales, dentro de las poblaciones occidentales de alto riesgo de enfermedad arterial.

Enfermedad de Chagas: indicador serológico y electrocardiografía convencional en un área urbana de región endémica (Deán Funes, Córdoba, Argentina) / Chagass disease

Para aportar información sobre la seropositividad para enfermedad de Chagas en un área urbana de zona endémica del noroeste de la provincia de Córdoba (República Argentina) se seleccionó una muestra de 983 habitantes de ambos sexos, entre 10 y 70 años. Se efectuó examen físico, un electrocardiograma convencional y extracción por punción digital de sangre para hemoaglutinación indirecta, prueba de inmunofluorescencia y detección cualitativa por enzimoinmunoensayo de anticuerpos anti-Trypanosoma cruzi (IgG). De los 983 individuos estudiados, el indicador serológico general (18,1 por ciento) fue bajo en las dos primeras décadas de edad estudiadas (10 a 29 años), aumentando paulatinamente hasta tener expresiones elevadas después de los 40 años. El reconocimiento del contacto con el triatoma, el haber tenido madre infectada y pobre condición socioeconómica, fueron riesgos que aumentaron la posibilidad de infección. Los seropositivos tuvieron porcentualmente mayor número de electrocardiogramas anormales, siendo el bloqueo completo de rama derecha, el hemibloqueo anterior izquierdo, el bloqueo completo de rama derecha más hemibloqueo anterior izquierdo y las extrasístoles ventriculares mono o polifocales repetitivas, los patrones más frecuentes (AU)

Enfermedad de Chagas: indicador serológico y electrocardiografía convencional en un área urbana de región endémica (Deán Funes, Córdoba, Argentina) / Chagas's disease

Para aportar información sobre la seropositividad para enfermedad de Chagas en un área urbana de zona endémica del noroeste de la provincia de Córdoba (República Argentina) se seleccionó una muestra de 983 habitantes de ambos sexos, entre 10 y 70 años. Se efectuó examen físico, un electrocardiograma convencional y extracción por punción digital de sangre para hemoaglutinación indirecta, prueba de inmunofluorescencia y detección cualitativa por enzimoinmunoensayo de anticuerpos anti-Trypanosoma cruzi (IgG). De los 983 individuos estudiados, el indicador serológico general (18,1 por ciento) fue bajo en las dos primeras décadas de edad estudiadas (10 a 29 años), aumentando paulatinamente hasta tener expresiones elevadas después de los 40 años. El reconocimiento del contacto con el triatoma, el haber tenido madre infectada y pobre condición socioeconómica, fueron riesgos que aumentaron la posibilidad de infección. Los seropositivos tuvieron porcentualmente mayor número de electrocardiogramas anormales, siendo el bloqueo completo de rama derecha, el hemibloqueo anterior izquierdo, el bloqueo completo de rama derecha más hemibloqueo anterior izquierdo y las extrasístoles ventriculares mono o polifocales repetitivas, los patrones más frecuentes