RESUMO
Follow-up clinical results have been analyzed for 564 patients with occlusions of visceral arteries, which presented clinically as symptoms of chronic pancreatitis in 115 patients. As a rule, chronic pancreatic ischemia leads to exocrine hyposecretion evident from the derangement of cyclonucleotide metabolism. There were also metabolic shifts in pancreatic cells related to hypoxia. Intravital biopsies revealed dystrophy of the acinar tissue as well as inter- and intralobular infiltrates of the connective and fatty tissue.
Assuntos
Isquemia/patologia , Pâncreas/irrigação sanguínea , Adulto , Amilases/sangue , AMP Cíclico/metabolismo , GMP Cíclico/metabolismo , Humanos , Lipase/sangue , Pessoa de Meia-Idade , Pâncreas/metabolismo , Pâncreas/patologia , Tripsina/sangue , Inibidores da Tripsina/sangueRESUMO
Considerable disturbances of the visceral blood circulation have been found to occur in stenosis of the celiac trunk. Circulatory disorders in the liver, pancreas, stomach and duodenum are dependent on the degree of the celiac trunk narrowing. The collateral vascular bed fails to provide the complete compensation of the reduced organic blood flow. As a result, chronic ischemia of the organs persists.