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1.
Int J Food Sci Nutr ; 75(3): 241-254, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38404064

RESUMO

Childhood stunting is a global phenomenon affecting more than 149 million children under the age of 5 worldwide. Exposure to aflatoxins (AFs) in utero, during breastfeeding, and consumption of contaminated food affect the gut microbiome, resulting in intestinal dysfunction and potentially contributing to stunting. This review explores the potential relationship between AF exposure, environmental enteropathy and childhood stunting. AFs bind to DNA, disrupt protein synthesis and elicit environmental enteropathy (EE). An EE alters the structure of intestinal epithelial cells, impairs nutrient uptake and leads to malabsorption. This article proposes possible intervention strategies for researchers and policymakers to reduce AF exposure, EE and childhood stunting, such as exposure reduction, the implementation of good agricultural practices, dietary diversification and improving environmental water sanitation and hygiene.


Assuntos
Aflatoxinas , Microbioma Gastrointestinal , Transtornos do Crescimento , Humanos , Aflatoxinas/toxicidade , Transtornos do Crescimento/etiologia , Microbioma Gastrointestinal/efeitos dos fármacos , Contaminação de Alimentos , Feminino , Enteropatias , Dieta , Pré-Escolar , Lactente , Exposição Ambiental/efeitos adversos , Gravidez , Exposição Dietética/efeitos adversos
2.
J Nutr Educ Behav ; 50(4): 408-414.e1, 2018 04.
Artigo em Inglês | MEDLINE | ID: mdl-29277491

RESUMO

OBJECTIVE: Geophagia, the deliberate consumption of rocks, soil, or clay, is prevalent in developing countries, particularly sub-Saharan Africa. Health risks associated with this behavior include parasitosis, heavy metal poisoning, nutrient deficiencies, and poor birth outcomes. This pilot study was designed to reduce geophagic practices and improve nutrition among rural Kenyan women. METHODS: The researchers used snowball sampling to recruit participants (n = 135; aged 15-49 years) from low socioeconomic areas who consumed geophagic materials. Interviews were carried out before and after a nutrition intervention implemented by trained community health volunteers. RESULTS: Nutrition education focusing on geophagia significantly (P < .001) decreased the practice in 77% of participants. Postintervention interviews also demonstrated substantial improvement in understanding the concept of making half the plate vegetables using the healthy plate model. CONCLUSIONS AND IMPLICATIONS: Nutrition education can be useful for reducing geophagia (a largely ignored, unsafe dietary behavior) and enhancing nutritional knowledge in African women.


Assuntos
Educação em Saúde/métodos , Conhecimentos, Atitudes e Prática em Saúde , Ciências da Nutrição/educação , Pica/prevenção & controle , Pica/psicologia , Adolescente , Adulto , Feminino , Humanos , Entrevistas como Assunto , Quênia , Pessoa de Meia-Idade , Projetos Piloto , População Rural , Adulto Jovem
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