A Dual-Path Cross-Modal Network for Video-Music Retrieval.

In recent years, with the development of the internet, video has become more and more widely used in life. Adding harmonious music to a video is gradually becoming an artistic task. However, artificially adding music takes a lot of time and effort, so we propose a method to recommend background music for videos. The emotional message of music is rarely taken into account in current work, but it is crucial for video music retrieval. To achieve this, we design two paths to process content information and emotional information between modals. Based on the characteristics of video and music, we design various feature extraction schemes and common representation spaces. In the content path, the pre-trained network is used as the feature extraction network. As these features contain some redundant information, we use an encoder-decoder structure for dimensionality reduction. Where encoder weights are shared to obtain content sharing features for video and music. In the emotion path, an emotion key frames scheme was used for video and a channel attention mechanism was used for music in order to obtain the emotion information effectively. We also added emotion distinguish loss to guarantee that the network acquires the emotion information effectively. More importantly, we propose a way to combine content information with emotional information. That is, content features are first stitched together with sentiment features and then passed through a fused shared space structured as an MLP to obtain more effective fused shared features. In addition, a polarity penalty factor has been added to the classical metric loss function to make it more suitable for this task. Experiments show that this dual path video music retrieval network can effectively merge information. Compared with existing methods, the retrieval task evaluation index increases Recall@1 by 3.94.

Baguan Therapy Is an Alternative in Treating Ankylosing Spondylitis: A Systematic Review Based on Existing Randomized Controlled Trials.

BACKGROUND: The aim of this systematic review was to evaluate the evidence available on the effects of Baguan therapy for ankylosing spondylitis (AS) patients. MATERIALS AND METHODS: The following databases were searched from their inception to August 2018: PubMed, Web of Science, AMED, Cochrane Library, Google, EMBASE, the China National Knowledge Infrastructure databases, Wanfang Data, CiNii, KoreaMed, and the Iranian Registry of Clinical Trials. Randomized controlled trials (RCTs), which assessed the effects of Baguan therapy for AS, were included in our review. The methodological quality of eligible studies was assessed by the Cochrane Collaboration's tool. The RevMan 5.3 software was used for quantitative analysis of RCTs. Heterogeneity was assessed using I2 statistics. RESULTS: Four studies were included in our review. The aggregated results indicated that Baguan therapy improved the treatment effect (risk ratio 1.21, 95% CI 1.10-1.34, p < 0.01) as well as physical function (Bath Ankylosing Spondylitis Functional Index) (mean difference -1.56, 95% CI -2.01 to -1.12, p < 0.01) and reduced disease activity (Bath Ankylosing Spondylitis Disease Activity Index) (mean difference -0.71, 95% CI -1.09 to -0.33, p < 0.01) in patients with AS. CONCLUSION: Due to the low quality of included trials, it is difficulty to draw the firm conclusion that Baguan therapy may have beneficial effects on AS.

[Cloning, eukaryotic expression and celluar localization of cysteine and glycine-rich protein 1].

OBJECTIVE: To construct an eukaryotic expression vector of pCMV-FLAG-CRP1 and investigate the cellular localization of cysteine and glycine-rich protein 1 (CRP1) in human embryonic kidney 293T, hepatocellular carcinoma HepG2 and breast cancer ZR75-1 cells. METHODS: Human CRP1 gene was obtained from mammary cDNA library by PCR and cloned into the pCMV-Tag2B vector. Human 293T, HepG2 and ZR75-1 cells were transfected with the recombinant plasmid pCMV-FLAG-CRP1; the expression was detected by Western blotting and the cellular localization was observed under a fluorescence microscope. RESULTS: CRP1 eukaryotic expression vector labeled with FLAG tag was successfully constructed as demonstrated by double enzyme digestion and gene sequencing. Western blotting showed that CRP1 protein was expressed in FLAG-CRP1 transfected 293T, HepG2 and ZR75-1 cells, and fluorescence microscopy revealed that CRP1 protein was localized in both cytoplasm and nucleus of the three cell lines, and the former signal was stronger than the latter. CONCLUSION: The eukaryotic expression vector of pCMV-FLAG-CRP1 is successfully constructed, and the cellular location of CRP1 is further identified in the 293T, HepG2 and ZR75-1 cell lines, which will contribute to the further study on the function of CRP1.