Assuntos
Adenoma/patologia , Pólipos Adenomatosos/patologia , Neoplasias Colorretais/patologia , Lesões Pré-Cancerosas/patologia , Adenoma/epidemiologia , Adenoma/cirurgia , Pólipos Adenomatosos/epidemiologia , Pólipos Adenomatosos/cirurgia , Adulto , Distribuição por Idade , Idoso , Idoso de 80 Anos ou mais , Biópsia por Agulha , Estudos de Coortes , Colectomia/métodos , Pólipos do Colo/epidemiologia , Pólipos do Colo/patologia , Pólipos do Colo/cirurgia , Neoplasias Colorretais/epidemiologia , Neoplasias Colorretais/cirurgia , Feminino , Humanos , Imuno-Histoquímica , Incidência , Masculino , Pessoa de Meia-Idade , Prognóstico , Estudos Retrospectivos , Medição de Risco , Distribuição por Sexo , Análise de Sobrevida , Resultado do TratamentoRESUMO
Low-grade lymphoma arising in mucosa-associated lymphoid tissue (MALT) of the duodenum represents a very rare neoplasm. We report an unusual presentation of primary duodenal MALT lymphoma in a 78-year-old man. The patient initially presented with a suspected pulmonary embolus and was anticoagulated, which precipitated a major gastrointestinal hemorrhage. A large atypical ulcer with narrowing of the duodenum beyond the bulb was seen on endoscopy. Biopsies revealed atypical lymphoid cells. Abdominal CT scan revealed a mass in either the duodenum or head of the pancreas. An endoscopic retrograde cholangiopancreatography (ERCP) was performed, which revealed a normal pancreatic duct with a large calculus in the common bile duct, which was extracted after sphincterotomy. Elective surgery was planned for suspected lymphoma of the duodenum. The patient developed severe nausea, vomiting, and fullness after meals. The patient underwent pancreaticoduodectomy for a neoplastic mass causing duodenal obstruction. Pathological examination of the resected specimen revealed a low-grade B-cell lymphoma (MALToma) arising in the duodenum and invading the pancreas. Flow cytometry confirmed the phenotype typical of MALT lymphoma. Celiac, peripancreatic, pelvic, and cervical nodes were also involved with tumor. Bone marrow was also positive for metastasis. The patient was postoperatively treated with chemotherapy for stage IV disease.
Assuntos
Neoplasias Duodenais/complicações , Neoplasias Duodenais/cirurgia , Obstrução da Saída Gástrica/cirurgia , Linfoma de Zona Marginal Tipo Células B/complicações , Linfoma de Zona Marginal Tipo Células B/cirurgia , Idoso , Terapia Combinada , Neoplasias Duodenais/diagnóstico , Neoplasias Duodenais/tratamento farmacológico , Obstrução da Saída Gástrica/etiologia , Humanos , Linfoma de Zona Marginal Tipo Células B/diagnóstico , Linfoma de Zona Marginal Tipo Células B/tratamento farmacológico , MasculinoRESUMO
Página que contiene imágenes endoscópicas del esófago, estómago, duodeno, endoscopia capsular, enfermedades inflamatorias del intestino, etc. Cada imágen incluye una breve explicación.
Assuntos
Endoscopia Gastrointestinal , Esôfago , Estômago , Duodeno , Doenças Inflamatórias Intestinais , Colo , Íleo , Endoscopia por CápsulaRESUMO
Somatostatinomas are extremely rare periampullary malignant neuroendocrine tumors that may be associated with von Recklinghausen disease or type-I neurofibromatosis. Duodenal somatostatinomas are distinguished from pancreatic somatostatinomas by their frequent association with type-I neurofibromatosis and typically absence of somatostatinoma syndrome. We report a very rare and atypical case of malignant duodenal somatostatinoma presenting with somatostatinoma syndrome in association with type-I neurofibromatosis.
