[Body constitution of patients of different somatotypes with hypertension]. / Komponenty tela u bol'nykh gipertonicheskoi bolezn'iu s razlichnym somatotipom.

Body constituents (cellular and extracellular mass, fat, extracellular fluid) were examined by means of K-40 whole-body radiometry in male essential hypertension patients with normal body weight and alimentary obesity. Second-stage essential hypertension was associated with a reduction of body cell mass, its relative parameters in particular. This fall was even more pronounced in patients with alimentary obesity. Apparently, increased proportion of fat in relation to body cell mass, which is more active metabolically, alters water-salt balance and, consequently, arterial blood pressure.

[Effect of cardiac glycosides on whole body potassium concentration in circulatory insufficiency]. / Deistvie serdechnykh glikozidov na soderzhanie obshchego kaliia tela pri nedostatochnosti krovoobrashcheniia.

Variation of potassium levels produced by cardiac glycosides was assessed in patients with 1st- to 3d-stage circulatory insufficiency, by means of 40K radioactivity measurement in a low radioactivity background chamber. Total group figures demonstrated that total body potassium levels increased with the improvement of the patients' clinical condition. Total body potassium decreased in patients showing signs of cardiac glycoside intoxication. The analysis of the data with reference to pre-and post-treatment baseline tissue potassium concentrations, as compared to the desired level, showed tissue potassium to normalize under the effect of cardiac glycosides in cases of initially abnormal values, and to decrease irrespective of the initial values in cases of cardiac glycoside intoxication.

[Influence of anti-arrhythmia agents on electrolyte metabolism]. / Vliianie antiaritmicheskikh sredstv na obmen elektrolitov

In 73 patients with hypertensive and ischemic heart diseases the total body potassium content was studied by measuring natural radioactivity with reference to K40 before and after administration of quinidine, isoptin and inderal. Furthermore, in 74 patients subject to determination was the blood plasma and erythrocytes potassium and sodium levels on application of the said agents. Following administration of quinidine and isoptin the level of total potassium in the organism was rising substantially, while taking inderal lead to a drop of the potassium concentration in the body. No clear cut parallels between the blood plasma and erythrocytes ontent and the level of total potassium in the organism could be uncovered. Mechanisms underlying the antiarrhythmic action of quinidine, isoptin and inderal are discussed.