[Comparison of invasive diagnostic techniques and revascularization therapy of acute coronary syndrome in Hungarian and international databases]. / Az akut coronariasyndromában alkalmazott invazív diagnosztika és terápia gyakorisága a magyar és a nemzetközi gyakorlatban (nemzetközi vizsgálatok adatai alapján).

UNLABELLED: INTRODUCTION, AIMS, METHODS: The databases of large multicentric trials dealing with acute coronary syndrome (OASIS Registry, CORE, PURSUIT, FRAX.I.S.) were analysed. RESULTS: Significant differences were disclosed comparing the baseline and history characteristics of patients randomized from Eastern or Western Europe. In most investigations the patients from Eastern Europe had a higher prevalence of hypertension, diabetes, angina and myocardial infarction. Invasive diagnostics and revascularization therapy were less frequently used in Eastern than in Western Europe in all the trials. The prevalence of myocardial infarction and the case fatality rate were not uniformly different during the early days, but after 30 days the case fatality rate in Eastern Europe was significantly higher than in Western Europe. CONCLUSION: It is suggested that the differences in demographic and baseline characteristics were only partially responsible for the difference in mortality. The low intervention rate and delayed revascularization may contribute to the high rate of myocardial infarction and mortality in Eastern Europe.