RESUMO
Abstract: Infantile myofibromatosis is a mesenchymal disorder characterized by the fibrous proliferation of the skin, bone, muscle and viscera. It is the most common fibrous tumor in childhood. We present a newborn with skin and bone disease without visceral involvement, who showed good response to vinblastine and methotrexate. Clinical features, etiology, diagnosis, and treatment are reviewed.
Assuntos
Humanos , Masculino , Recém-Nascido , Miofibromatose/congênito , Vimblastina/uso terapêutico , Imuno-Histoquímica , Metotrexato/uso terapêutico , Resultado do Tratamento , Miofibromatose/patologia , Miofibromatose/tratamento farmacológico , Fármacos Dermatológicos/uso terapêuticoRESUMO
Infantile myofibromatosis is a mesenchymal disorder characterized by the fibrous proliferation of the skin, bone, muscle and viscera. It is the most common fibrous tumor in childhood. We present a newborn with skin and bone disease without visceral involvement, who showed good response to vinblastine and methotrexate. Clinical features, etiology, diagnosis, and treatment are reviewed.