[Developmental cysts in the presacral space in adults]. / Quistes del desarrollo en el espacio presacro en el adulto.

Localization of primitive neoplasms the retrorectal or presacral space is rare in adults as most of these tumors are congenital. Developmental cysts are included within the group of retrorectal congenital cystic neoplasms and are slowly-progressive cystic neoplasms. Because of their localization, their manifestation is delayed, despite their congenital nature. Their form of presentation is varied and is caused by compression of the surrounding organs or infectious complications of the cyst.We describe two cases of presacral developmental cysts (one epidermoid cyst and one dermoid cyst) that presented in adulthood. Special attention is paid to the classification, and diagnostic and therapeutic problems of these tumors.

[Prognostic value of nuclear DNA of 106 colorectal tumors, determined with microspectrocytophotometry]. / Valor pronóstico del ADN nuclear de 106 tumores colorrectales, medido por microespectrocitofotometría.

OBJECTIVE: The aim of this study was to look for correlations between nuclear DNA content of colo-rectal tumors, and such clinical parameters as age, sex, location, CEA, histological grade and Duke's stages. EXPERIMENTAL DESIGN: A prospective study is carried out on surgical patients, subjected to standard criteria of radicality. Nuclear DNA content was quantified in tumoral cells by microcytophotometric techniques. PATIENTS: 106 patients with colo-rectal cancer. Patients with colonic perforation, other concomitant neoplasia, non-curative surgery or receiving adjuvant therapies were excluded from the study. Five patients died during the postoperative period and one was lost. RESULTS: Histological grade: 28% G1, 35% G2 and 37% G3. Dukes': 8% A, 40% B, 32% C and 20% D. DNA quantification has rendered 45% as euploid and 55% as aneuploid. There was no statistical correlation between ploidy and location, age, sex or CEA. However, there is a clear preponderance of euploid tumors in G1 (23 vs. 5), while the aneuploid tumors double the euploid ones (24 and 25 vs. 12 and 12) in G2 and G3. A similar result was found comparing ploidy and Dukes: euploid tumors reach 77% both in stages A and B, while they drop to 24% and 14% in stages C and D. It has also been found that euploid tumors show a longer period of survival free of recurrence. CONCLUSIONS: Evidence has been found supporting a prognostic value for tumoral DNA quantification in colo-rectal cancer. A longer follow-up is required to study absolute survival of the patients.

[Effect of body weight and acute mesenteric ischemia duration on the mortality of rats subjected to intestinal revascularization]. / Influencia del peso corporal y del período de isquemia mesentérica aguda en la mortalidad de ratas sometidas a revascularización intestinal.

We have studied the influence of corporal weight and acute mesenteric ischemia (AMI) duration on the mortality and average survival of rats submitted to intestinal revascularization. The results demonstrated that mortality is under 50% when the AMI is equal or less than 2 hours. There are also important differences in mortality, for the same AMI duration, depending on the corporal weight and age of the animals. The differences are statistically significant up to 210 g. In conclusion, in experimental studies on intestinal ischemia-revascularization, it is necessary to correct for factors as ischemia duration and weight, which are variables that can alter the results.

[Cecal actinomycosis: apropos of a case]. / Actinomicosis cecal: a propósito de un caso.

A case is presented of abdominal actinomycosis restricted to the cecum, with the appendix and terminal ileum spared. We analyze the clinical and diagnostic aspects, with their differential diagnoses, as well as medico-surgical therapeutic options.