Ectodermal dysplasia: important role of complex dental care in its interdisciplinary management.

AIM: Despite the fact that ectodermal dysplasia (ED) is a rare disease, it is often seen in a tertiary clinic. ED affects ectodermal tissues such as skin, hair, teeth, nails, and sweat glands. Patients usually have sparse light hair, deformed nails, and dry skin. They suffer from dental abnormalities such as oligodontia (absence of 6 or more teeth) or complete anodontia; salivation can also be affected. The absence of teeth can be the overriding problem for both patients and their parents, and lead to substantial social ostracisation. This study aims to summarise the facts about the disease, especially dental treatment options based on data drawn from a representative Czech cohort. MATERIALS: The present article summarises the facts about ectodermal dysplasia (ED) in a cohort of 13 patients, where the following were evaluated: clinical manifestations of ED, pathogenic variants detected in selected candidate genes and dental treatment options from child removable dentures to fixed crowns and implants insertion. Three cases are described in detail and demonstrate approaches for different age groups. CONCLUSION: Early diagnosis and active cooperation between the geneticist and dentist will facilitate cooperation with parents and patients and assure secondary prevention. It is preferable that the geneticist understands dental treatment options and can discuss these with patients/parents.

Immediate dentin sealing: effect of sandblasting on the layer thickness.

OBJECTIVES: The objective of this study was to observe and to measure the impact of corundum sandblasting on the thickness of the Immediate dentin sealing layer. METHODS: 20 recently extracted molars were collected and divided randomly into two groups. A standardized preparation was performed on each tooth and the Optibond FL dentin bonding agent (Kerr, Orange, USA) was applied on the prepared surface according to the manufacturer's instructions. The surface was then partially sandblasted. RONDOflex plus 360 (KaVo, Bieberach an der Riss, Germany) and Airsonic Mini-Sandblaster (Hager et Werken, Duisburg, Germany) were used. Microscope observations were made. RESULTS: The arithmetic mean of the Optibond FL dentin bonding agent film thickness was 48.72 µm (Group 1=45.55 µm and Group 2=51.88 µm). The dentin bonding agent layer thickness was reduced to the average value of 17,12 µm by RONDOflex plus 360 sandblasting (Group 1). The zero value was recorded in 16 % of the locations. The Airsonic Mini-Sandblaster sandblasting changed the average thickness of the dentin bonding agent layer to 13.25 µm with 31 % of zero values (Group 2). CONCLUSION: The results of this research lead to a reflection on modifications of the immediate dentin sealing procedure (Tab. 4, Fig. 3, Ref. 28).

Prospective longitudinal study of early childhood caries and developmental defects of enamel on permanent successors in children in the Czech Republic.

AIM: This study investigates the influence of early childhood caries (ECC) on the occurence of developmental defects of enamel (DDE) on permanent teeth. METHODS: Study design: This prospective original study was conducted to monitor the relationship between ECC in primary dentition and DDE as their consequences on permanent successors. One hundred and forty children were recruited and included in the study group with diagnosed ECC (ECCG) (N=60) or the control group (CG) (N=80). Deciduous upper central incisors were assessed for existing dental caries according to the dmft index and the modified pufa score and permanent incisors were examined using the modified DDE index. RESULTS: Prevalence of DDE was 19.3% in the whole sample; in ECCG it was 24.2% and 12.6% in CG. The most common defect was diffuse opacity with a prevalence of 44.8% in ECCG and 72% in CG. Prevalence of hypoplasia was 13.8% in ECCG, in CG it was present as a combination defect with a prevalence of 4%. The extent of less than 1/3 of labial aspect was in 69% of defects in ECCG,in CG it was 52%. The location of defects in the incisal third was 48.3% in ECCG and 32% in controls. CONCLUSION: A statistically significant relationship between ECC and DDE was not observed. The results were compared with studies about the relationship between ECC and DDE.