Recent Trends in Plastic Surgery: A Network Analysis of the Abstract Titles of the Largest German Plastic Surgery Congress 2023.

BACKGROUND: Every year, German-speaking experts in plastic, reconstructive, and aesthetic surgery gather to discuss the latest developments at Germany's largest conference for plastic surgery, the joint annual meeting of the German Society of Plastic, Reconstructive and Aesthetic Surgery (DGPRÄC) and the Association of German Aesthetic Plastic Surgeons (VDÄPC). Since the topics of the conference have a lasting impact on the practice and research of plastic surgery, an examination of the presented content provides insight into the driving developments in plastic surgery in Germany. MATERIALS AND METHODS: We conducted a retrospective network analysis of all abstract titles from the DGPRÄC and VDÄPC annual meeting in 2023. Data were extracted regarding titles, language, author, and place of origin, and the titles were categorized into the four pillars of the specialty. The titles were standardized and subjected to network analysis. RESULTS: A total of 299 titles from 281 lectures and 18 instructional courses were analyzed. After preprocessing the data, 2463 words with 9384 connections qualified for network analysis. The most frequently mentioned keywords throughout the congress were 'Surgery', 'Breast', 'Reconstruction', 'Flap', 'Patient', 'Tissue', and 'Therapy'. Locations contributing the highest number of abstracts were Ludwigshafen, Hanover, Leipzig, and Munich. CONCLUSION: In the era of big data, network analysis provides the ability to identify underlying structures and nodes in multidimensional, complex datasets. This study demonstrates the useful application of network analysis to identify thematic focuses and connections at the current DGPRÄC and VDÄPC annual meeting. Sites of intensified research could thus be identified.

Esthetic outcome after nasal reconstruction with paramedian forehead flap and bilobed flap.

The incidence of skin cancer, which often affects the facial skin, has risen worldwide. After resecting such facial lesions, plastic reconstruction is necessary in most cases. The paramedian forehead flap (PFF) and the bilobed flap (BF) are commonly used for nasal reconstruction, but whether patients and physicians are satisfied with the esthetics is undetermined? In this study, scar questionnaires (Manchester Scar Scale, Vancouver Scar Scale, and Patient and Observer Scar Assessment Scale) and optical three-dimensional (3D) imaging were used for subjective and objective evaluation of esthetical outcomes after plastic reconstruction of the nose in 30 patients. The distances between landmarks and changes in volume between the treated and both the mirrored, healthy side of the face as well as an untreated, matched control group were measured using the optical (3D) scans. The questionnaires ascertained whether the patient was content with the esthetical outcome of both flaps. In the opinion of the observer, the esthetical outcome of both flaps was sufficient; only a few of the measured distances differed significantly between the patients and the control group. However, the measured volume differences of the donor site of the flap differed significantly between the PFF group and the control group (p = 0.0078). The BF was used for smaller defects, while the PFF was used for major defects. Besides a greater donor-side morbidity for the PFF, both flaps led to esthetically sufficient results and could be used for the reconstruction of the nose depending on the defect size and localization.

Gammopathy interference in clinical chemistry assays: mechanisms, detection and prevention.

Monoclonal gammopathy is characterized by the presence of an M-protein in serum or urine that has homogeneous structural and functional properties. It can occur in very high concentrations and may cause significant interference in clinical chemistry assays. Examples of gammopathy interference for the analytes glucose, bilirubin, gamma-glutamyltransferase, urea and ferritin are presented. Various mechanisms of interference are described, such as the production of turbidity by the M-protein and the binding of the M-protein to a component of the test system or analyte. In immunoglobulin tests, the M-protein is the analyte itself and may not be completely bound by the test antibody owing to its structural properties. Modern analyzers can detect unusual changes in absorption during the course of a reaction, and thus the formation of turbidity due to M-proteins. This interference may be prevented by optimizing the buffering conditions of the reagents to avoid the formation of turbidity or by removal of the M-protein prior to analysis of the sample. Owing to the unique properties of each M-protein, it is impossible to protect common clinical chemistry test systems completely from gammopathy interference. Therefore, efficient ways for the detection of such interference are needed.