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1.
Eat Weight Disord ; 7(2): 124-30, 2002 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-17644866

RESUMO

This study investigated the presence of the False Consensus Effect (FCE) with body and shape-related attitudes in 30 normal weight women who scored high or low on a measure of concern with body shape. The participants were asked to rate depressive, positive, neutral, and body shape self-statements for relevance to self and to others. They also estimated the percentage of individuals that would agree with each attitudinal statement. Women with high body shape concerns rated themselves and others as significantly more likely to agree with the statements expressing such concerns than those with low concerns. They also believed that a significantly higher percentage of others would favor those attitudes. This pattern of findings is supportive of the presence of a FCE in normal weight women preoccupied with body shape and size.


Assuntos
Atitude , Imagem Corporal , Transtornos da Alimentação e da Ingestão de Alimentos/psicologia , Percepção Social , Análise de Variância , Feminino , Humanos , Distorção da Percepção , Autoimagem
2.
Arch Environ Contam Toxicol ; 40(2): 192-7, 2001 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-11243321

RESUMO

The vascular macrophyte Typha latifolia Linnaeus (common cattail) may be a sentinel for evaluating potential phytotoxicity to rooted aquatic macrophytes in aquatic systems. To further evaluate the potential utility of this species, T. latifolia seed germination, shoot growth, and root elongation were measured in 7-day aqueous exposures using mean measured aqueous copper concentrations of 10.0, 23, 41, 62, 174, and 402 microg Cu/L, which were > or = 62% of nominal concentrations. Seed germination and seedling shoot growth were not significantly affected by any of these copper concentrations as compared to controls. Mean measured no-observed-effect-concentration (NOEC) and lowest-observed-effect-concentration (LOEC) for root elongation were 18.6 microg Cu/L and 35.0 microg Cu/L, respectively. Seven-day sediment tests were conducted by amending uncontaminated sediments with copper sulfate to mean measured concentrations of 7.9, 17.1, 21.0, 51.2, 89.5, and 173.5 mg Cu/kg, which were > or = 84% of nominal concentrations. Seed germination was not significantly different from controls. Mean measured NOEC and LOEC values for seedling shoot growth were 89.5 mg Cu/kg and 173.5 mg Cu/kg, respectively, and mean measured NOEC and LOEC values for root growth were 14.0 mg Cu/kg and 19.7 mg Cu/kg, respectively. These results demonstrate that T. latifolia early seedling growth can be utilized for assessing aqueous and sediment toxicity of copper.


Assuntos
Sulfato de Cobre/farmacologia , Germinação/efeitos dos fármacos , Poaceae/crescimento & desenvolvimento , Sementes/crescimento & desenvolvimento , Poaceae/efeitos dos fármacos , Sementes/efeitos dos fármacos , Poluentes do Solo/análise , Poluentes Químicos da Água/análise
3.
Child Abuse Negl ; 25(11): 1415-26, 2001 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-11766008

RESUMO

OBJECTIVE: The purpose was to explore the effects of victim/complainant and perpetrator/defendant gender on the impact of recovered memory testimony in criminal sexual abuse trials. METHOD: A jury simulation methodology was used. Two hundred forty-six participants read a summary of a sexual abuse trial in which the following three variables were manipulated: the complainant's gender, the defendant's gender, and whether the complainant's memory of the alleged abuse had been "recovered" or remembered all along. Participants reached a verdict and rated the culpability and credibility of the parties. RESULTS: Compared to a case where the memory of the abuse had always been remembered, recovered memory testimony led to lower perceptions of the defendant's culpability and higher perceptions of the defendant's credibility. In addition, the complainant with recovered memory was viewed as less credible and less likely to be telling the truth. These effects of testimony type (i.e., recovered vs. remembered) were qualified by an interaction with complainant and defendant gender, such that testimony type exerted an effect in cases of alleged heterosexual but not homosexual abuse. CONCLUSION: The results suggest that mock jurors' judgments in sexual abuse cases reflect their stereotypes about sexual abuse and expectations regarding the relative likelihood of repression in various circumstances.


Assuntos
Vítimas de Crime/psicologia , Transtornos da Memória/terapia , Delitos Sexuais/psicologia , Adulto , Vítimas de Crime/legislação & jurisprudência , Direito Penal/legislação & jurisprudência , Feminino , Humanos , Transtornos da Memória/psicologia , Recuperação de Função Fisiológica , Repressão Psicológica , Fatores Sexuais
4.
Free Radic Biol Med ; 29(7): 612-9, 2000 Oct 01.
Artigo em Inglês | MEDLINE | ID: mdl-11033413

RESUMO

Little is known concerning the effect of oxidative stress on the expression of antioxidative enzymes in the decompensated cardiac hypertrophy of spontaneously hypertensive rats (SHR), considered as a model of dilative cardiomyopathy in man. Superoxide dismutase (SOD), catalase, and glutathione peroxidase (GPx) were characterized in isolated perfused hearts of 18 month old SHR and the age-matched normotensive control Wistar-Kyoto (WKY) rats, before and after 30 min infusion of 25 microM H(2)O(2). After infusion of H(2)O(2), aortic flow decreased in WKY from 26.2 +/- 2.2 to 16.0 +/- 0.8 ml/min (p <.05) but not in SHR (18.2 +/- 1.9 vs. 20.7 +/- 2.2 ml/min). This protection was related to the higher myocardial activities of GPx, MnSOD and CuZnSOD in SHR, compared with those of the WKY group. Although total SOD activity in the SHR fell after H(2)O(2) exposure (to 1.81 +/- 0.13 from 3.56 +/- 0.49 U/mg of protein), catalase activity increased (to 2.46 +/- 0.34 from 1.56 +/- 0.29 k min(-1)mg(-1)protein), compared with the pre-infusion period (p <.05 in each case). In additional studies, hearts were subjected to 30 min of global ischemia followed by 30 min of reperfusion. The results obtained in ischemic/reperfused hearts show the same changes in enzyme activities measured as it was observed in H(2)O(2) perfused hearts, indicating that oxidative stress is independent of the way it was induced. The higher catalase activity derived from elevated mRNA synthesis. The antioxidative system in dilative cardiomyopathic hearts of SHR is induced, probably due to episodes of oxidative stress, during the process of decompensation. This conditioning of the antioxidative potential may help overcome acute stress situations caused by reactive oxygen species in the failing myocardium.


Assuntos
Catalase/genética , Regulação Enzimológica da Expressão Gênica/fisiologia , Glutationa Peroxidase/genética , Peróxido de Hidrogênio/farmacologia , Hipertensão/enzimologia , Miocárdio/enzimologia , Estresse Oxidativo , Superóxido Dismutase/genética , Animais , Catalase/metabolismo , Regulação Enzimológica da Expressão Gênica/efeitos dos fármacos , Glutationa Peroxidase/metabolismo , Hipertensão/genética , Masculino , RNA Mensageiro/genética , Ratos , Ratos Endogâmicos SHR , Ratos Endogâmicos WKY , Reação em Cadeia da Polimerase Via Transcriptase Reversa , Superóxido Dismutase/metabolismo , Transcrição Gênica/efeitos dos fármacos
5.
Proc Natl Acad Sci U S A ; 97(23): 12655-60, 2000 Nov 07.
Artigo em Inglês | MEDLINE | ID: mdl-11035814

RESUMO

To address the dual needs for improved methods to assess potential health risks associated with chemical exposure in aquatic environments and for new models for in vivo mutagenesis studies, we developed transgenic fish that carry multiple copies of a bacteriophage lambda vector that harbors the cII gene as a mutational target. We adapted a forward mutation assay, originally developed for lambda transgenic rodents, to recover cII mutants efficiently from fish genomic DNA by lambda in vitro packaging. After infecting and plating phage on a hfl- bacterial host, cII mutants were detected under selective conditions. We demonstrated that many fundamental features of mutation analyses based on lambda transgenic rodents are shared by transgenic fish. Spontaneous mutant frequencies, ranging from 4.3 x 10(-5) in liver, 2.9 x 10(-5) in whole fish, to 1.8 x 10(-5) in testes, were comparable to ranges in lambda transgenic rodents. Treatment with ethylnitrosourea resulted in concentration-dependent, tissue-specific, and time-dependent mutation inductions consistent with known mechanisms of action. Frequencies of mutants in liver increased insignificantly 5 days after ethylnitrosourea exposure, but increased 3.5-, 5.7- and 6. 7-fold above background at 15, 20, and 30 days, respectively. Mutants were induced 5-fold in testes at 5 days, attaining a peak 10-fold induction 15 days after treatment. Spontaneous and induced mutational spectra in the fish were also consistent with those of lambda transgenic rodent models. Our results demonstrate the feasibility of in vivo mutation analyses using transgenic fish and illustrate the potential value of fish as important comparative animal models.


Assuntos
Bacteriófago lambda/genética , Genes Virais , Mutagênese , Oryzias/genética , Fatores de Transcrição/genética , Animais , Animais Geneticamente Modificados , Análise Mutacional de DNA/métodos , Etilnitrosoureia/farmacologia , Estudos de Viabilidade , Mutagênese/efeitos dos fármacos , Mutagênicos/farmacologia , Proteínas Virais
6.
Behav Modif ; 23(4): 556-77, 1999 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-10533440

RESUMO

Research testing the predictions of cognitive-behavioral theory related to the psychopathology of eating disorders has lagged behind treatment outcome research. Central to cognitive theories of eating disorders is the hypothesis that beliefs and expectancies pertaining to body size and to eating are biased in favor of selectively processing information related to fatness/thinness, dieting, and control of food intake or body weight. In recent years, controlled investigations of the predictions of cognitive theories of eating disorders have yielded empirical support for these theories. This paper reviews research which has tested the predictions of cognitive-behavioral theory and discusses the implications of these findings for the treatment of eating disorders. Understanding of information processing biases may assist the clinician in understanding a range of psychopathological features of anorexia and bulimia nervosa, including denial, resistance to treatment, and misinterpretation of therapeutic interventions.


Assuntos
Atitude , Terapia Cognitivo-Comportamental/tendências , Mecanismos de Defesa , Transtornos da Alimentação e da Ingestão de Alimentos/psicologia , Transtornos da Alimentação e da Ingestão de Alimentos/terapia , Comportamento Obsessivo/psicologia , Constituição Corporal , Imagem Corporal , Humanos , Modelos Psicológicos , Escalas de Graduação Psiquiátrica
7.
J Med Entomol ; 26(3): 190-9, 1989 May.
Artigo em Inglês | MEDLINE | ID: mdl-2566686

RESUMO

Natural populations of Culiseta melanura (Coquillett) and Cs. morsitans (Theobald) were marked and released at three sites associated with the Toad Harbor-Big Bay Swamp eastern equine encephalitis (EEE) virus focus in central New York. Collections of Culiseta from surveillance sites within 12.8 km of the release sites were screened for marked specimens. A total of 172 marked specimens were recaptured. The majority of recaptured mosquitoes were collected at sites associated with the swamp complex, but some were collected at seven of the eight recapture sites, up to 9.8 km from a release site. The distances traveled by 103 recaptured individuals were used to calculate the mean distance traveled and flight ranges for sexes and cohorts of both species. The mean distance traveled for females that were marked and released from resting shelters was 4 km for Cs. melanura and 5 km for Cs. morsitans. The mean distance traveled for females marked and released from a CDC + CO2 light trap was 9 km and 8 km for Cs. melanura and Cs. morsitans, respectively. The flight ranges of these species overlap the EEE epizoötic zone, and the results of these studies support the hypothesis that these species are involved in the transfer of EEE virus from swamp to upland habitats.


Assuntos
Culicidae/fisiologia , Encefalomielite Equina/transmissão , Insetos Vetores/fisiologia , Animais , Vírus da Encefalite Equina do Leste/fisiologia , Feminino , Masculino
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