[Secondary metabolites of mangrove endophytic fungus BL321 in the South China Sea].

OBJECTIVE: To study the secondary metabolites of mangrove endophytic fungus BL321. METHODS: The compounds were isolated by chromatographic technique. The structures were identified by comprehensive physico-chemical properties and spectral methods. RESULTS: Five compounds were isolated and identified as 3,4a-dimethyl-2-oxo-2,4,4a,5,6,7-hexahydronaphtho[2,3-b]furan-5-carboxylic acid(1), cytochalasin C(2), cytochalasin D(3), 19,20-epoxycytochalasin C(4), ergosterol(5). CONCLUSION: Compound 1 is isolated from nature for the first time. Further more, several kinds of strong bioactive compounds were islolate from this fungus indicate that it may develop to be medical source microorganism.