Caries prevalence and experience in individuals with osteogenesis imperfecta: A cross-sectional multicenter study.

OBJECTIVE: Dentinogenesis Imperfecta (DI) forms a group of dental abnormalities frequently found associated with Osteogenesis Imperfecta (OI), a hereditary disease characterized by bone fragility. The objectives of this study were to quantify the dental caries prevalence and experience among different OI-types in the sample population and quantify how much these values change for the subset with DI. METHODS: To determine which clinical characteristics were associated with increased Caries Prevalence and Experience (CPE) in patients with OI, the adjusted DFT scores were used to account for frequent hypodontia, impacted teeth and retained teeth in OI population. For each variable measured, frequency distributions, means, proportions and standard deviations were generated. Groups means were analyzed by the unpaired t-test or ANOVA as appropriate. For multivariate analysis, subjects with caries experience of zero were compared with those with caries experience greater than zero using logistic regression. RESULTS: The stepwise regression analysis while controlling for all other variables demonstrated the presence of DI (OR 2.43; CI 1.37-4.32; P = 0.002) as the significant independent predictor of CPE in the final model. CONCLUSION: This study found no evidence that CPE of OI subjects differs between the types of OI. The presence of DI when controlled for other factors was found to be the significant predictor of CPE.

Oral health-related quality of life in children and adolescents with osteogenesis imperfecta: cross-sectional study.

BACKGROUND: Osteogenesis imperfecta (OI) affects dental and craniofacial development and may therefore impair Oral Health-Related Quality of Life (OHRQoL). However, little is known about OHRQoL in children and adolescents with OI. The aim of this study was to explore the influence of OI severity on oral health-related quality of life in children and adolescents. METHODS: Children and adolescents aged 8-14 years were recruited in the context of a multicenter longitudinal study (Brittle Bone Disease Consortium) that enrolls individuals with OI in 10 centers across North America. OHRQoL was assessed using the Child Perceptions Questionnaire (CPQ) versions for 8 to 10-year-olds (CPQ8-10) and for 11 to 14-year-olds (CPQ11-14). RESULTS: A total of 138 children and adolescents (62% girls) diagnosed with OI types I, III, IV, V and VI (n = 65, 30, 37, 4 and 2, respectively) participated in the study. CPQ8-10 scores were similar between OI types in children aged 8 to 10 years. In the 11 to 14-year-old group, CPQ11-14-scores were significantly higher (i.e. worse) for OI types III (24.7 [SD 12.5]) and IV (23.1 [SD 14.8]) than for OI type I (16.5 [SD 12.8]) (P < 0.05). The difference between OI types was due to the association between OI types and the functional limitations domain, as OI types III and IV were associated with significantly higher grade of functional limitations compared to OI type I. CONCLUSION: The severity of OI impacts OHRQoL in adolescents aged 11 to 14 years, but not in children age 8 to 10 years.

Evaluation of sexual dimorphism in maxillary and mandibular canine using mesiodistal, labiolingual dimensions, and crown height.

CONTEXT: Gender estimation is one of the most important parameters in forensic identification. Teeth being the central component of the masticatory apparatus of the skull is a good source of material for civil and medico-legal purpose. Gender estimation using dental features is primarily based on the comparison of tooth dimensions in male and female. AIMS: To analyze the presence of sexual dimorphism in maxillary and mandibular canine using mesiodistal (MD), labiolingual (LL), and height of crown. SUBJECTS AND METHODS: A total number of 100 subjects (50 males and 50 females) were included in the study between the age group of 20 and 25 years. Dimensions (MD, LL, height of crown) of maxillary and mandibular canine were recorded with a digital vernier calliper. STATISTICAL ANALYSIS USED: The data obtained is subjected to statistical analysis using Student's t-test and intra-reliability test. RESULTS: The present study revealed that male shows larger mean dimensions of teeth than female. Out of all the four canines, right maxillary canine shows highly consistent results for sexual dimorphism. Hence, by drawing the conclusion, it can be stated that right maxillary canine can be used as an adjunct along with other procedures for gender estimation. CONCLUSION: The findings support the usefulness of employing odontometric analysis of the canine teeth in gender estimation. It is an easy, reproducible, and objective method.