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1.
Intervirology ; 21(4): 181-6, 1984.
Artigo em Inglês | MEDLINE | ID: mdl-6329992

RESUMO

Cricket paralysis virus was shown to share common antigen(s) with encephalomyocarditis virus (Cardiovirus: Picornaviridae), a virus normally associated with mammals. These viruses must be regarded now as being related strains of one and the same virus. These results pose interesting questions for the taxonomy and ecology of small RNA viruses.


Assuntos
Vírus da Encefalomiocardite/classificação , Vírus de Insetos/classificação , Ortópteros/microbiologia , Picornaviridae/classificação , Animais , Antígenos Virais/análise , Reações Cruzadas , Vírus da Encefalomiocardite/imunologia , Vírus de Insetos/imunologia , Picornaviridae/imunologia , Picornaviridae/isolamento & purificação
7.
J Clin Pathol ; 27(6): 495-9, 1974 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-4370087

RESUMO

Direct immunofluorescence staining for herpes simplex virus was applied to cryostat sections of 43 specimens removed at brain biopsy. Herpes antigen was found in 10 specimens and virus was isolated from them. Antigen was found in one specimen from which virus was not isolated. Two specimens from which virus was isolated gave equivocal fluorescence. Thirty specimens gave no fluorescence or live virus. Immunofluorescence provided a diagnosis in three hr compared with 24-42 hr for virus isolation. Indirect immunofluorescence staining was applied to sections of brain removed at necropsy and fixed in formalin. Herpes antigen was found in sections of six of the 12 brains examined.


Assuntos
Encefalite/diagnóstico , Herpes Simples/diagnóstico , Animais , Antígenos Virais/análise , Autopsia , Biópsia , Encéfalo/microbiologia , Encefalite/microbiologia , Imunofluorescência/métodos , Herpes Simples/microbiologia , Humanos , Coelhos/imunologia , Simplexvirus/imunologia , Simplexvirus/isolamento & purificação , Fatores de Tempo
19.
Br Med J ; 4(5738): 776-80, 1970 Dec 26.
Artigo em Inglês | MEDLINE | ID: mdl-4925077

RESUMO

The antiviral effect of 5% idoxuridine in dimethyl sulphoxide intermittently applied and of 40% idoxuridine in dimethyl sulphoxide continuously applied for four days to the lesions in patients with zoster of recent onset was studied in two double-blind controlled trials. Most, but not all, of the patients receiving intermittent active treatment had pain for a short period only. The effect of continuous treatment was striking: pain had disappeared within nine days in all the patients and healing was accelerated. The results were statistically significant.


Assuntos
Dimetil Sulfóxido/uso terapêutico , Herpes Zoster/tratamento farmacológico , Idoxuridina/uso terapêutico , Adulto , Idoso , Contagem de Células Sanguíneas , Criança , Ensaios Clínicos como Assunto , Formas de Dosagem , Feminino , Humanos , Idoxuridina/administração & dosagem , Masculino , Pessoa de Meia-Idade
20.
J Hyg (Lond) ; 68(3): 411-6, 1970 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-4318814

RESUMO

The sera of 308 patients, not suffering from varicella or zoster infections, and the sera of 183 blood donors were examined for complement-fixing antibody to varicella-zoster virus. In both groups about 70% of sera from persons aged 11-40 years had antibody titres >/= 1/4; the incidence was less in the age range 41-60 years and increased in later decades. Antibody titres of 1/16 or 1/32 were noticeably less frequent in those aged 41-60 years than in younger or older groups.It was concluded that an unchanging titre of 1/16 or 1/32 was of no diagnostic significance. The age distribution of antibody was consistent with the theory that zoster only occurs when antibody has declined.


Assuntos
Anticorpos/análise , Herpesvirus Humano 3/imunologia , Adolescente , Adulto , Idoso , Especificidade de Anticorpos , Antígenos , Doadores de Sangue , Criança , Pré-Escolar , Testes de Fixação de Complemento , Humanos , Lactente , Pessoa de Meia-Idade , Pacientes , Simplexvirus/imunologia
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