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1.
Toxins (Basel) ; 14(12)2022 12 09.
Artigo em Inglês | MEDLINE | ID: mdl-36548762

RESUMO

The aim was to evaluate the effect of feeding a low-phosphorus and maintenance protein diet in healthy cats and cats with chronic kidney disease (CKD) with IRIS stages 1 (CKD-1) and 2 (CKD-2). Cats were initially fed a senior diet (30 days) followed by the renal diet (60 days). Body composition, body weight (BW), muscle mass score (MMS), and body condition score (BCS) were assessed before (T30) and after renal diet intake (T60). General mixed linear models were used to assess the effects of fixed groups and moments (T30 × T60), as well as their interaction, in addition to the random effects of animals within each group. Unlike healthy cats and cats with CKD-1, cats with CKD-2 had a loss of BW, lower BCS (p < 0.005), and lower MMS (p = 0.0008) after 60 days of consuming the renal diet. The fat mass and lean body mass (LBM), determined by the deuterium isotopes method, did not change in all cats between T0 and T60. In healthy cats and cats with CKD-1, the renal diet resulted in maintenance of BW, BCS and MMS; but cats with CKD-2 presented lower BCS and did not reduce phosphatemia after consumption.


Assuntos
Fósforo , Insuficiência Renal Crônica , Gatos , Animais , Dieta/veterinária , Peso Corporal , Insuficiência Renal Crônica/veterinária , Composição Corporal
2.
Br J Nutr ; 120(7): 777-786, 2018 10.
Artigo em Inglês | MEDLINE | ID: mdl-30132436

RESUMO

The source of starch may interfere with glycaemic control in dogs, but few studies have evaluated these aspects in diabetic dogs. This study compared the effects of two isonutrient diets with different starch sources, peas and barley (PB) v. maize (Mi), on diabetic dogs. The Mi diet was processed in order to generate a lower starch gelatinisation index. In all, fifteen adult diabetic dogs without other conditions were included. The animals were fed two dry extruded rations with moderate levels of fat and starch and high levels of protein and fibre using a random, double-blind cross-over design. Glycaemic curves over 48 h were developed via continuous glucose monitoring after 60 d on each diet and with the same neutral protamine Hagedorn (NPH) insulin dosage. The following were compared: fasting, mean, maximum and minimum blood glucose, maximum and minimum glycaemia difference, glycaemic increment, area under the glycaemic curve, area under the glycaemic increment curve and serum fructosamine concentration. Paired t tests or Wilcoxon signed-rank tests were used to compare the amount of food and nutrients ingested and the dietary effects on glycaemic variables between the diets. Dogs fed the PB diet presented a lower average mean interstitial glucose (P=0·01), longer mean hypoglycaemic time (P<0·01), shorter mean hyperglycaemic time (P<0·01) and smaller difference between maximum and minimum blood glucose levels (P=0·03). Thus, the processing applied to the Mi diet was not sufficient to achieve the same effects of PB on glycaemic control in diabetic dogs.


Assuntos
Glicemia/metabolismo , Diabetes Mellitus/sangue , Dieta , Hordeum/química , Pisum sativum/química , Amido/farmacologia , Zea mays/química , Animais , Área Sob a Curva , Carboidratos da Dieta/sangue , Carboidratos da Dieta/farmacologia , Fibras na Dieta/administração & dosagem , Proteínas Alimentares/administração & dosagem , Cães , Método Duplo-Cego , Jejum , Feminino , Frutosamina/sangue , Hiperglicemia/sangue , Hiperglicemia/etiologia , Hiperglicemia/prevenção & controle , Hipoglicemia/sangue , Hipoglicemia/etiologia , Hipoglicemia/prevenção & controle , Hipoglicemiantes/farmacologia , Masculino , Distribuição Aleatória , Amido/sangue
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