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Skinmed ; 15(1): 17-25, 2017.
Artigo em Inglês | MEDLINE | ID: mdl-28270305

RESUMO

Chronic ulcers are defined as a breakdown of the long-term cutaneous barrier or frequent recurrence of breakdowns. Dressings are a form of treatment and, in view of the variety and high cost of the products on the market, three agents were selected for this investigation, regarding their efficacy and cost/benefit ratio. The objective of the investigation was to evaluate and compare the efficacy, costs, and benefits of carboxymethylcellulose in paste at 20% (CMC 20%), trichloroacetic acid at 90% (TCA 90%), and Unna boot for treatment of chronic venous ulcers. Three groups of 30 patients each were chosen randomly for ambulatory treatment with TCA 90% (G1), CMC 20% (G2), and Unna boot (G3). The evolution of the cicatricial process of each group separately and between groups was analyzed with measurement of the lesion areas in square centimeters (cm2) and observation of the amount of exudate from observation of the photographic record, until their healing, in the maximum period of 20 weeks. A significant reduction of lesion areas in all groups was observed (P=.0001), with a median reduction of 7.6 cm2 (38.1%) for G1, 3.9 cm2 (38.8%) for G2, and 16.2 cm2 (77.8%) for G3. There was a significant difference in the absolute delta of the lesion areas (P=.0001) of the groups. The three types of treatments promoted effective improvement, with acquisition and utilization of all three products in the public health services being recommended.


Assuntos
Carboximetilcelulose Sódica/uso terapêutico , Gelatina/uso terapêutico , Glicerol/uso terapêutico , Ácido Tricloroacético/uso terapêutico , Úlcera Varicosa/diagnóstico , Úlcera Varicosa/terapia , Cicatrização/efeitos dos fármacos , Compostos de Zinco/uso terapêutico , Administração Cutânea , Assistência Ambulatorial/métodos , Bandagens/economia , Carboximetilcelulose Sódica/economia , Doença Crônica , Estudos de Coortes , Combinação de Medicamentos , Feminino , Seguimentos , Gelatina/economia , Glicerol/economia , Humanos , Masculino , Recidiva , Estudos Retrospectivos , Medição de Risco , Índice de Gravidade de Doença , Fatores Socioeconômicos , Fatores de Tempo , Resultado do Tratamento , Ácido Tricloroacético/economia , Compostos de Zinco/economia
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