RESUMO
A practical and accurate method of determining ovulation using cervical mucus is described. Ovulatory cycles from 32 healthy women were assessed using hormonal and nonhormonal methods. Cervical mucus extractable immunoglobulins were assayed for the complete cycles of nine women and randomly collected from 23 additional women with normal cycles. All normal ovulatory women showed a minimum concentration present at midcycle when optimum conditions for fertilization existed. Using newer laser nephelometry techniques, the content of extractable immunoglobulin G and immunoglobulin A per sample weight confirmed the cyclic nature of the concentration of immunoglobulin in cervical mucus, and correlated well with previously defined biophysical properties of cervical mucus. Nephelometry proved to be rapid, accurate, and an inexpensive technique for determining ovulation and has potential for clinical use.
Assuntos
Muco do Colo Uterino/imunologia , Imunoglobulinas/análise , Detecção da Ovulação/métodos , Adulto , Feminino , Humanos , Imunodifusão , Lasers , Menstruação , Nefelometria e Turbidimetria/métodosRESUMO
Circulating plasma levels of human prothrombin antigen and activity were determined in normal pregnancy and in pregnancies complicated by hypertension, eclampsia, or preeclampsia. The ratio of prothrombin antigen to activity (Ag/Act) was within normal limits for all hypertensive patients. However, every untreated preeclamptic patient, as well as 2 eclamptic patients, had abnormal prothrombin antigen to activity ratios.
Assuntos
Antígenos/análise , Coagulação Sanguínea , Pré-Eclâmpsia/sangue , Protrombina/imunologia , Eclampsia/sangue , Feminino , Humanos , Hipertensão/sangue , Gravidez , Complicações Cardiovasculares na Gravidez/sangueRESUMO
Vaginal agenesis in association with an intact and functioning or partially functioning uterus is not a well-described problem. The literature advocates attempting to preserve the uterus and surgically create a neovagina. Two patients are presented who suffered severe mobidity after the latter approach. We believe that there are three possibilities with patients who have functional endometrial tissue with vaginal agenesis: namely, an imperforate hymen, a transverse vaginal septum or complete vaginal agenesis with the absence or malformation of the cervix. If an imperforate hymen and transverse vaginal septum are ruled out, we believe it is the best interest of the patient to remove the Müllerian structures during the initial surgery.
