Assuntos
Fármacos Gastrointestinais/uso terapêutico , Obstrução Intestinal/tratamento farmacológico , Obstrução Intestinal/cirurgia , Octreotida/uso terapêutico , Fármacos Gastrointestinais/administração & dosagem , Humanos , Obstrução Intestinal/etiologia , Intestinos/efeitos dos fármacos , Intestinos/patologia , Neoplasias/complicações , Neoplasias/cirurgia , Octreotida/administração & dosagem , Cuidados Pré-OperatóriosRESUMO
Gastrointestinal obstruction is a common problem in advanced malignant disease, but its management remains controversial. In those patients for whom surgery is not appropriate, medical intervention is the only remaining option. We present a series of 14 patients with intestinal obstruction who were managed with subcutaneous injections of octreotide, a somatostatin analogue which reduces the volume of gastrointestinal secretions. Good control of vomiting was achieved in 12 patients, and no major side effects were observed. Octreotide would appear to be a useful drug in this clinical situation.
Assuntos
Obstrução Intestinal/complicações , Neoplasias/fisiopatologia , Octreotida/uso terapêutico , Vômito/tratamento farmacológico , Idoso , Feminino , Suco Gástrico/efeitos dos fármacos , Suco Gástrico/metabolismo , Humanos , Injeções Subcutâneas , Intubação Gastrointestinal , Masculino , Pessoa de Meia-Idade , Octreotida/administração & dosagem , Cuidados Paliativos , Vômito/etiologiaRESUMO
Home care is greatly expanding because of the savings it offers by avoiding unnecessary hospitalization and also because patients benefit from being in their own home environments. Since 1988, Societa Assistenza Malato Oncologico Terminale (SAMOT) has organized a pain relief and home palliative care unit for terminal cancer patients. Objectives, difficulties, protocols, and achievements of 4 years of experience were examined, and the findings of the various years were compared. Our results suggest that considerable progress has been made in home palliative care. There are still social and cultural difficulties to overcome, however.