RESUMO
The efficacy of boehmite (Rocgel) and of ranitidine was compared in a randomized, double-blind 4-week trial in patients with symptomatic, endoscopically free macroscopic reflux oesophagitis. Of the 64 patients who completed the study 33 received boehmite and 31 ranitidine. Significant symptomatic improvement occurred in both treatment groups (global clinical score and self evaluation by patients) (p < 0.001). Disappearance of heartburn was 52 per cent (15/29) with boehmite and 53 per cent (16/30) with ranitidine. Disappearance of regurgitation was 48 per cent (10/21) with both treatments. 33% of the patients became totally symptom-free. Our results indicate that boehmite seems to be at least as effective as ranitidine in relieving symptoms. Cost of treatment with boehmite, on the other hand is cheaper than ranitidine. As a safe, locally active mucosal protecting agent and antacid, boehmite is an effective drug for the treatment of reflux oesophagitis without macroscopic lesions.
Assuntos
Hidróxido de Alumínio/uso terapêutico , Óxido de Alumínio/uso terapêutico , Refluxo Gastroesofágico/tratamento farmacológico , Antagonistas dos Receptores H2 da Histamina/uso terapêutico , Ranitidina/uso terapêutico , Adolescente , Adulto , Idoso , Hidróxido de Alumínio/administração & dosagem , Óxido de Alumínio/administração & dosagem , Método Duplo-Cego , Feminino , Refluxo Gastroesofágico/diagnóstico , Humanos , Masculino , Pessoa de Meia-Idade , Ranitidina/administração & dosagem , Fatores de TempoRESUMO
The prevention of the rectum and colon carcinoma consists principally in the radioendoscopic detection of colonic polyps. The double contrast enema is the best method for this detection. The usual practice of double contrast imposes the restatement of a comfortable method for the patient, simple and reliable for the doctor. The authors mean in this study to compare two groups of patients (group I and II) which differ by the double contrast technique used. If the colonic preparation, the injection implements and the investigation preliminaries are the same in both groups, there is no evacuation time of the barium enema which is added to trimebutine and stopped to the left iliac crest are specific with this method. The results allows an accuracy diagnosis of polyps.
Assuntos
Sulfato de Bário , Meios de Contraste/administração & dosagem , Neoplasias do Colo/diagnóstico por imagem , Enema , Humanos , Pólipos Intestinais/diagnóstico por imagem , Radiografia , Neoplasias Retais/diagnóstico por imagem , TrimebutinaAssuntos
Úlcera Duodenal/cirurgia , Omento/cirurgia , Úlcera Péptica Perfurada/cirurgia , Vagotomia/métodos , Idoso , Animais , Cães , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Técnicas de SuturaAssuntos
Circulação Assistida/métodos , Hipertensão Portal/cirurgia , Veias Mesentéricas/cirurgia , Veia Cava Inferior/cirurgia , Adulto , Idoso , Prótese Vascular , Varizes Esofágicas e Gástricas/complicações , Varizes Esofágicas e Gástricas/etiologia , Feminino , Hemorragia Gastrointestinal/etiologia , Humanos , Hipertensão Portal/complicações , Masculino , Pessoa de Meia-IdadeAssuntos
Doenças Retais , Úlcera , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Doenças Retais/patologia , Reto/patologia , Úlcera/patologiaAssuntos
Endoscopia/métodos , Hemorragia Gastrointestinal/diagnóstico , Adulto , Endoscópios , Humanos , Intestino Delgado , MasculinoRESUMO
Important progress in the last few years in fiberscopic instrumentation for digestive endoscopy has made possible duodenoscopy with catheterization of the papilla to obtain retrograde biliopancreatic contrast x-rays. Up to now the only possible way to explore biliary ducts, in icterus, was surgically. This new method makes their study possible without any surgical intervention and with a simple neuroleptanalgesia. It is most advantageous in icterus where clinical tests, laboratory tests and other complementary examinations such as laparoscopy do not help to determine the cause. This examination is not devoid of dangers, particularly of the risk of cholangitis and pancreatitis and therefore certain technical precautions are necessary, e.g., immediate surgical intervention in case of organ obstruction and well defined indications.