Outcomes of Transurethral Resection of Prostate in Patients with and without Renal Failure Secondary to an Enlarged Prostate.

The natural history of benign enlargement of the prostate is variable and ranges from mild symptoms to chronic retention and renal failure. In this study, the outcomes of patients with urinary retention alone were compared with those of chronic retention and renal failure caused by an enlarged prostate. The first group had 79, while the second group had 20 patients included. The mean maximum flow rate after transurethral resection of the prostate (TURP) in the two groups was 16.9 ± 7.9 vs. 14.6 ± 4.1 ml/sec (p value > 0.05), and the mean post-void volume was 15.1 ± 27.6 vs. 21.7 ± 35.7 ml (p value > 0.05), respectively. However, the residual symptoms after surgery were higher in the chronic retention group. It was concluded that patients, with chronic retention experience and higher postoperative residual storage symptoms, after transurethral resection of the prostate, are able to void without a catheter and their renal functions were stabilised. Key Words: Transurethral resection of the prostate, Prostatic hyperplasia, Renal insufficiency, Urinary bladder neck obstruction.

A 37-year-old woman with refractory coeliac disease type II disease treated by stem cell transplantation.

This case study describes the disease course and treatment of a rare disorder, refractory coeliac disease. This disorder is associated with a marked increase in the risk of development of enteropathy-associated T-cell lymphoma. The patient in question developed coeliac symptoms despite strict adherence to a gluten-free diet, having been symptom-free for over 7 years. She presented with marked oedema of the legs and a distended abdomen. Investigations--laboratory, radiological and enteroscopy findings--were consistent with the development of refractory coeliac disease. This case illustrates the background and course of this disease, and the treatment options.