Home Use of Mini-Dose Glucagon As a Novel Treatment for Hypoglycemia Following Repeated, Prolonged Fasts in Type 1 Diabetes During Ramadan.

OBJECTIVE: We determined the efficacy of self-administered subcutaneous mini-dose glucagon (MDG) to treat fasting-induced hypoglycemia in type 1 diabetes (T1D). RESEARCH DESIGN AND METHODS: This was a 4-week randomized, controlled crossover trial of 2-week MDG or 2-week oral glucose tablets (OG, control) involving 17 adults with T1D during Ramadan. RESULTS: Compared with OG, MDG demonstrated a significant higher change in blood glucose from baseline to 30 min (Δt30, P < 0.001) and 1 h (Δt60, P = 0.02). The efficacy of MDG was preserved following ≥8 h fasting with significantly higher Δt30 in MDG (P = 0.01). Over the entire 2 weeks, MDG period had increased time in 70-180 mg/dL (P = 0.009) and less time <70 mg/dL (P = 0.04). MDG use resulted in higher completion of fasts compared with OG (P < 0.001). CONCLUSIONS: MDG administration is an effective alternative to OG for prevention and treatment of fasting-induced hypoglycemia, offering improved glycemic control and promoting successful completion of prolonged fasts.

Evaluating the relationship between smartphone addiction/overuse and musculoskeletal pain among medical students at Qassim University.

BACKGROUND: Smartphone use has greatly increased in recent days, and most of the daily tasks are done through these devices. As a result, long time use may involve bad posture that may result in musculoskeletal pain. Therefore, it is important to evaluate the association between addiction/overuse of smartphones and musculoskeletal pain. AIM: To determine the prevalence of addictive/overuse of smartphones among medical students and to investigate if there is an association between smartphone addiction and musculoskeletal pain. METHOD: A cross-sectional study conducted at Qassim University, medical college. The Smartphone Addiction Scale Short Version (SAS-SV) was used to measure the level of smartphone addiction while the Nordic musculoskeletal questionnaire (NMQ) was utilized to evaluate the musculoskeletal pain. RESULTS: The prevalence of smartphone addiction among medical students was relatively high (60.3%). The most frequent pain related to smartphone addiction was in the neck (60.8%), followed by lower back (46.8%), shoulder (40.0%). The academic year level was statistically associated with the level of smartphone addiction. Moreover, we found a significant relationship between musculoskeletal pain and smartphone addiction at certain body regions, neck, wrist/hand and knees, Other musculoskeletal parameters included in the test were found to have no statistically significant association. CONCLUSION: More than half of the medical students identified as addicted to smartphones. The most common musculoskeletal pain was the neck, lower back, and shoulder. The academic year level found to have a significant association with the level of smartphone addiction while musculoskeletal pain such as neck, wrist, and knee were the independent significant factors of smartphone addiction; therefore, it is important to educate the community about the effect of being addicted to smartphone use in order to prevent the consequences of this behavior.