Discrimination and psychological distress among Asian Americans during COVID-19: Gender differences in the moderating role of social support.

Our study aimed to assess the role of social support on the impact of discrimination on psychological distress for Asian American women and men. Using the Asian American sample from the Asian American and Native Hawaiian/Pacific Islander COVID-19 Needs Assessment Study (n = 3,508), we used logistic regression to examine the moderating role of different types of social support on the relationship between discrimination and psychological distress by gender. Among Asian Americans, facing discrimination was associated with higher odds of psychological distress, and receiving emotional support was associated with lower odds of psychological distress. When examining interactions between discrimination, social support, and gender, we found that facing discrimination led to the highest odds of psychological distress for Asian American women who provided emotional support. Our findings highlight different mechanisms by which social support buffers and exacerbates the psychological burden of discrimination for Asian Americans. These findings have overall and gender-informed implications for community policies to promote mental health resilience by actively alleviating the effects of racism among Asian Americans. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Lower Doses of Fructose Extend Lifespan in Caenorhabditis elegans.

Epidemiological studies indicate that the increased consumption of sugars including sucrose and fructose in beverages correlate with the prevalence of obesity, type-2 diabetes, insulin resistance, hyperinsulinemia, hypertriglyceridemia, and hypertension in humans. A few reports suggest that fructose extends lifespan in Saccharomyces cerevisiae. In Anopheles gambiae, fructose, glucose, or glucose plus fructose also extended lifespan. New results presented here suggest that fructose extends lifespan in Caenorhabditis elegans (C. elegans) wild type (N2). C. elegans were fed standard laboratory food source (E. coli OP50), maintained in liquid culture. Experimental groups received additional glucose (111 mM), fructose (55 mM, 111 mM, or 555 mM), sucrose (55 mM, 111 mM, or 555 mM), glucose (167 mM) plus fructose (167 mM) (G&F), or high fructose corn syrup (HFCS, 333 mM). In four replicate experiments, fructose dose-dependently increased mean lifespan at 55 mM or 111 m Min N2, but decreased lifespan at 555 mM (P < 0.001). Sucrose did not affect the lifespan. Glucose reduced lifespan (P < 0.001). Equal amount of G&F or HFCS reduced lifespan (P < 0.0001). Intestinal fat deposition (IFD) was increased at a higher dose of fructose (555 mM), glucose (111 mM), and sucrose (55 mM, 111 mM, and 555 mM). Here we report a biphasic effect of fructose increasing lifespan at lower doses and shortening lifespan at higher doses with an inverse effect on IFD. In view of reports that fructose increases lifespan in yeast, mosquitoes and now nematodes, while decreasing fat deposition (in nematodes) at lower concentrations, further research into the relationship of fructose to lifespan and fat accumulation in vertebrates and mammals is indicated.