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1.
Retin Cases Brief Rep ; 17(3): 239-241, 2023 May 01.
Artigo em Inglês | MEDLINE | ID: mdl-34580248

RESUMO

PURPOSE: To report the clinical and optical coherence tomography findings of a patient with chronic central serous chorioretinopathy who developed a short-term bacillary layer detachment after photodynamic therapy (PDT). METHODS: A 56-year-old man presented with metamorphopsia and 20/100 visual acuity in his right eye. He was diagnosed with active, chronic central serous chorioretinopathy based on clinical findings and multimodal imaging. His visual problems and retinal findings persisted for 3 months before he was treated with half-fluence, half-dose verteporfin PDT. RESULTS: The patient had a prominent decrease in his vision postoperatively. Two days after treatment, multimodal imaging showed a marked increase in exudation that merged preoperative neurosensory retinal detachments. A prominent subfoveal bacillary layer detachment was also present. The subretinal fluid and bacillary layer detachment resolved over the next 8 weeks, with a return of visual acuity to its baseline level and normalization of retinal structures except for a small zone of subfoveal ellipsoid zone and interdigitation zone disruption. CONCLUSION: Half-fluence, half-dose verteporfin PDT caused a fulminant increase in subretinal fluid and an associated subfoveal bacillary layer detachment. We hypothesize that chronic central serous chorioretinopathy-related chorioretinal dysfunction contributed to the severe PDT-induced local inflammatory reaction that caused the patient's bacillary layer detachment. Hyperacute choroidal exudation too fulminant for containment in subretinal space extended into and exceeded photoreceptor inner segment tensile strength, cleaving the myoid layer and/or dissecting it from the ellipsoid layer. This finding broadens the causality spectrum of bacillary layer detachments and vision losses that can follow PDT.


Assuntos
Bacillus , Coriorretinopatia Serosa Central , Fotoquimioterapia , Porfirinas , Masculino , Humanos , Pessoa de Meia-Idade , Verteporfina/uso terapêutico , Coriorretinopatia Serosa Central/diagnóstico , Fármacos Fotossensibilizantes/uso terapêutico , Fotoquimioterapia/métodos , Tomografia de Coerência Óptica , Angiofluoresceinografia , Estudos Retrospectivos , Doença Crônica
2.
Retina ; 42(10): e48-e49, 2022 10 01.
Artigo em Inglês | MEDLINE | ID: mdl-36129271
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