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Food Chem Toxicol ; 182: 114116, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-37923193

RESUMO

Spices are contaminated with aflatoxins (AFs) and Sudan dyes which are classified as class Group 1 and Group 3 human carcinogens by the International Agency for Research on Cancer (IARC) respectively and their prolonged exposure may raise a human health concern. A total of 474 samples of red chili and turmeric were collected from Lahore city and were subjected to quantitative and qualitative AFs and Sudan dyes analysis by thin layer chromatography (TLC) respectively. The number of red chili and turmeric samples with ≥10 µg/kg of total AFs (European Union standard limit) were 70% and 33% respectively and considered unfit for human consumption. The presence of Sudan dyes in red chili and turmeric samples was 67% and 27% respectively. The mean estimated daily intake (EDI) among females and males was 0.0019 µg/kg bw/day, 0.0012 µg/kg bw/day for red chili, and 0.0008 µg/kg bw/day, 0.0006 µg/kg bw/day for turmeric respectively. The mean value of margin of exposure (MOE) among females and males for ingestion of AFs-contaminated red chili and turmeric was 210.25, 332.13, 501.02, and 699.31 respectively. Therefore, the current study demands a continuous monitoring plan and the implementation of novel techniques to enhance the product's quality and protect public health.


Assuntos
Aflatoxinas , Corantes , Humanos , Corantes/toxicidade , Aflatoxinas/toxicidade , Aflatoxinas/análise , Curcuma , Paquistão , Contaminação de Alimentos/análise , Cromatografia Líquida de Alta Pressão/métodos
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