[Lipoid necrobiosis in the practical work of a therapist and dermatologist].

This paper deals with the main aspects of etiology and pathogensis, clinical picture and therapy of lipoid necrobiosis. A case of successful treatment of the disease that developed long before clinical and laboratory manifestations of disturbed carbohydrate metabolism is reported.

[Comparative analysis of methods for laboratory diagnosis of Lyme's disease in early stages of infection]. / Sravnitel'nyi analiz metodov laboratornoi diagnostiki bolezni laima na rannei stadii infektsii.

Different methods of laboratory diagnostics were comparatively analyzed in examining 25 patients at the early infection stage. Sera were measured by using various serological reactions. Specific antibodies were determined by using the reaction of indirect immune-fluorescence (RIIF), the immune-enzyme analysis (IEA) and the complement-binding reaction (CBR) in 83.1%, 54.4% and 12.5% of cases, respectively. Essential differences in sensitivity were detected between the above methods. RIIF was proven to be a reliable and sufficiently sensitive method in the laboratory diagnostics of Lyma's disease. While the use of two methods, i.e. RIIF and IEA, ensures the highest percentage of detection of antibodies to the causative agent of Lyma's disease.

[Morphology of the skin manifestations of Lyme disease]. / K morfologii kozhnykh proiavlenii bolezni Laima.

The paper describes a case of a long-lasting chronic migrant erythema (ME) in an 82-year-old female, which developed after the bite of an insect (a tick?). The specific feature of this case is an unusual duration (2 years) of a single focus of ME and autopsy of the skin revealed giant cells with centrally arranged 3-5 nuclei and cytoplam with PAS-positive inclusions as tiny (5 m) oblong formations, that may be Borelia.