RESUMO
Thirty-one patients who received a prolonged maintenance therapy with cordarone to treat and prevent cardiac arrhythmias underwent an ophthalmologic examination. The treatment lasted 1.5 to 51 months. The signs of keratopathy were detected in 24 (77.4%) patients using a slit lamp biomicroscopy. There is a relationship between the severity of keratopathy and a daily dose of cordarone: in most cases signs of stage I keratopathy were detectable when the daily dose was up to 200 mg. Keratopathy appears to be reversible after the drug has been discontinued.
Assuntos
Amiodarona/administração & dosagem , Arritmias Cardíacas/tratamento farmacológico , Doenças da Córnea/induzido quimicamente , Adulto , Idoso , Amiodarona/efeitos adversos , Arritmias Cardíacas/prevenção & controle , Relação Dose-Resposta a Droga , Seguimentos , Humanos , Pessoa de Meia-Idade , Fatores de TempoRESUMO
Based on the estimation of results of the complex treatment of 88 patients with chronic nonspecific sialodenitis the authors have established high therapeutic efficiency of the radiation of a low energy laser in threshold doses resulting in rapid liquidation of inflammatory symptoms and pain, high salivation, longer remission and a recovery of the gland structure.