RESUMO
Solitary infantile myofibroma is a benign fibrous tumor occurring in early childhood. Although rare, it is the most common benign fibrous tumor of infancy. The clinical course of the disease is almost uniformly good since most tumors regress spontaneously. When indicated, conservative surgical excision is the treatment of choice, with a low recurrence rate. We present a case of solitary infantile myofibroma that recurred after three attempts of surgical excision, questioning the reported recurrence rate and the standard of care in recurrent solitary infantile myofibroma.
RESUMO
Childhood granulomatous periorificial dermatitis (CGPD), considered a clinical variant of perioral dermatitis, typically affects prepubertal children of African descent. It is a condition of unknown etiology characterized by the presence of a monomorphic yellow-brown papular eruption limited to the perioral, perinasal, and periocular regions that histopathologically shows a granulomatous pattern. This disorder should be differentiated from other conditions as granulomatous rosacea, sarcoidosis, and lupus miliaris disseminatus faciei. We report a case of a 9-year-old boy who presented with flesh-colored perorificial papules on the face, evolving for two months. Upon treatment with topical tacrolimus for follicular eczema, an aggravation of the condition was observed. A skin biopsy confirmed the diagnosis of CGPD. Our patient was successfully treated with a combination of topical metronidazole and topical erythromycin.
Assuntos
Dermatite Perioral/patologia , Granuloma/patologia , Administração Tópica , Anti-Infecciosos/uso terapêutico , Biópsia , Criança , Dermatite Perioral/tratamento farmacológico , Quimioterapia Combinada , Eritromicina/uso terapêutico , Face/patologia , Granuloma/tratamento farmacológico , Humanos , Imunossupressores/efeitos adversos , Masculino , Metronidazol/uso terapêutico , Pele/patologia , Tacrolimo/efeitos adversosRESUMO
UNLABELLED: We report two rare cases of Bellini duct carcinoma, a rare variant of renal cell carcinoma. CASE 1: The patient, a 73-year-old female, was admitted to the hospital for macroscopic hematuria and right flank pain. She was diagnosed to have a stage IV Bellini duct carcinoma. There was a progression of the disease despite chemotherapy. She died 21 months later. CASE 2: The patient, an 81-year-old male, was admitted to the hospital for generalized fatigue, weight loss and left flank pain. He was diagnosed to have a stage IV Bellini duct carcinoma. The patient was treated with chemotherapy; he died six months later. We report the clinicopathological features of two cases of Bellini duct carcinoma in order to contribute to the related literature of this rare disease.
