[The effect of metacin on the activity of digestive enzymes participating in the hydrolysis of fats normally and in stress]. / Vliianie metatsina na aktivnost' pishchevaritel'nykh fermentov, uchastvuiushchikh v gidrolize zhirov, v norme i pri stresse.

The effect of a peripheral cholinolytic methacin on the activity of lipolytic enzymes of the pancreas and small intestine was studied on intact and stress-exposed animals. The drug was shown to induce certain changes in the activity of lipolytic enzymes. The preliminary administration of methacin attenuates the shifts in the activity of the studied enzymes observed under stress action.

[Effect of metatsin on digestive enzyme activity]. / Vliianie metatsina na aktivnost' nekotorykh pishchevaritel'nykh fermentov.

The effect of a peripheral cholinergic blocking agent on the activity of some digestive enzymes involved in protein hydrolysis was studied on albino rats under normal conditions and during stress. Metacine was administered orally. Single doses were 100, 200 and 300 mg/kg. At long-term administration and in the subsequent series of experiments the dose was 200 mg/kg. The experiments showed that the drug treatment produced significant changes in the activity of digestive enzymes involved in protein hydrolysis. A preliminary administration of metacine was found to smooth out the changes in the activity of the enzymes observed under conditions of immobilization and hyperthermia.

[Effect of amizil on the activity of enzymes participating in protein hydrolysis in intact animals and animals subjected to stress exposure]. / Vliianie amizila na aktivnost' fermentov, uchastvuiushchikh v gidrolize belkov, u intaktnykh i podvergnutykh stressovomu vozdeistviiu zhivotnykh.

The effect of amizil on the activity of digestive enzymes involved in the initial and final stages of protein hydrolysis was studied on intact and stress exposed rats. The experiments showed that amizil administration produced varying changes in the activity of proteases and dipeptidase. At the same time a preliminary administration of the drug was found to prevent the changes in the enzyme activity observed during stress situations.