[Gastrointestinal tract microflora in nonspecific ulcerative colitis]. / Mikroflora zheludochno-kishechnogo trakta pri nespetsificheskom iazvennom kolite.

The species and quantitative composition of the normal and conditionally pathogenic microflora of the stomach, the proximal portion of the small intestine, in material obtained by biopsy from the mucosa of this portion, and in feces was studied in 10 patients with non-specific ulcerative colitis. The study was made before and after treatment. Before treatment in most of the patients gastric juice and the proximal portion of the small intestine were found to be greatly contaminated with microflora commonly present in feces, and in fecal microflora sharp dysbiotic changes were observed. As a result of treatment the microflora was essentially normalized (with the exception of Proteus and bifidobacteria).

[Method of determining the microbial flora of the small intestinal cavity and mucosa in different gastrointestinal tract diseases]. / K metodike opredeleniia mikrobnoi flory polosti i slizistoi obolochki tonkoi kishki pri razlichnykh zabolevaniiakh zheludochno-kishechnogo trakta.

Intestinal microflora in patients with chronic enterocolitis and duodenal ulcer was studied. Both the cavity of the small intestine and the structures of its mucosa were investigated. The method of aspiration biopsy was used, the samples of multiple washings of the intestinal mucosa and its homogenate were used for seeding. The results thus obtained in indicated that the structures of the mucosa contained microorganisms similar to those isolated from the intestinal cavity, but in lesser amounts and with different characteristics. The proposed method of detecting the microflora in the intestinal cavity and mucosa is simple and can be used in clinical practice.