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1.
Reumatologia ; 59(2): 111-114, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-33976465

RESUMO

Coexistence of spondyloarthritis (SpA) and Takayasu's arteritis is not a common finding, but such cases have been discussed, particularly in the context of choice of therapy. Inhibition of inflammation by tumor necrosis factor inhibitors (TNFi) is a key aspect of the treatment of SpA and also positive effects of such treatment in concomitant large vessel vasculitis have been reported. However, TNFi is also associated with the possibility of initiating vasculitis. The present article based on a case study and the available literature is an attempt to discuss coexistence of these two diseases and the impact of treatment with biological drugs from the anti-TNF group in the course of SpA with Takayasu's arteritis.

2.
Emerg Infect Dis ; 9(6): 665-71, 2003 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-12781005

RESUMO

An outbreak of serogroup W-135 meningococcal disease occurred during the 2000 Hajj in Saudi Arabia. Disease was reported worldwide in Hajj pilgrims and their close contacts; however, most cases were identified in Saudi Arabia. Trends in Saudi meningococcal disease were evaluated and the epidemiology of Saudi cases from this outbreak described. Saudi national meningococcal disease incidence data for 1990 to 2000 were reviewed; cases from January 24 to June 5, 2000, were retrospectively reviewed. The 2000 Hajj outbreak consisted of distinct serogroup A and serogroup W-135 outbreaks. Of 253 identified cases in Saudi Arabia, 161 (64%) had serogroup identification; serogroups W-135 and A caused 93 (37%) and 60 (24%) cases with attack rates of 9 and 6 cases per 100,000 population, respectively. The 2000 Hajj outbreak was the first large serogroup W-135 meningococcal disease outbreak identified worldwide. Enhanced surveillance for serogroup W-135, especially in Africa, is essential to control this emerging epidemic disease.


Assuntos
Surtos de Doenças , Infecções Meningocócicas/epidemiologia , Neisseria meningitidis Sorogrupo W-135/isolamento & purificação , Aniversários e Eventos Especiais , Demografia , Feminino , Humanos , Islamismo , Masculino , Neisseria meningitidis/classificação , Arábia Saudita/epidemiologia , Sorotipagem , Viagem
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